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- NCIT_C91430 NCIT_NHC0 "C91430" @default.
- NCIT_C91430 NCIT_P106 "Functional Concept" @default.
- NCIT_C91430 NCIT_P108 "Autophagy Regulation Pathway" @default.
- NCIT_C91430 NCIT_P208 "CL422157" @default.
- NCIT_C91430 NCIT_P215 "hsa04140" @default.
- NCIT_C91430 NCIT_P325 "Autophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily conserved among eukaryotes and exquisitely regulated. This progress initiates with production of the autophagosome, a double-membrane intracellular structure of reticular origin that engulfs cytoplasmic contents and ultimately fuses with lysosomes for cargo degradation. Autophagy is regulated in response to extra- or intracellular stress and signals such as starvation, growth factor deprivation and ER stress. Constitutive level of autophagy plays an important role in cellular homeostasis and maintains quality control of essential cellular components." @default.
- NCIT_C91430 normalizedInformationContent "73.604245822873736" @default.
- NCIT_C91430 referenceCount "54" @default.
- NCIT_C91430 hasExactSynonym "Autophagy - animal" @default.
- NCIT_C91430 hasExactSynonym "Autophagy Regulation Pathway" @default.
- NCIT_C91430 hasExactSynonym "Regulation of autophagy" @default.
- NCIT_C91430 type Class @default.
- NCIT_C91430 isDefinedBy ncit.owl @default.
- NCIT_C91430 label "Autophagy Regulation Pathway" @default.
- NCIT_C91430 subClassOf NCIT_C18611 @default.
- NCIT_C91430 subClassOf NCIT_C20633 @default.
- NCIT_C91430 subClassOf NCIT_C39702 @default.
- NCIT_C91430 subClassOf NCIT_C91430 @default.