Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C91476> ?p ?o ?g. }
Showing items 1 to 17 of
17
with 100 items per page.
- NCIT_C91476 NCIT_NHC0 "C91476" @default.
- NCIT_C91476 NCIT_P106 "Functional Concept" @default.
- NCIT_C91476 NCIT_P108 "Fc Epsilon Receptor I Signaling Pathway KEGG" @default.
- NCIT_C91476 NCIT_P207 "C2984288" @default.
- NCIT_C91476 NCIT_P215 "hsa04664" @default.
- NCIT_C91476 NCIT_P325 "Fc epsilon RI-mediated signaling pathways in mast cells are initiated by the interaction of antigen (Ag) with IgE bound to the extracellular domain of the alpha chain of Fc epsilon RI. The activation pathways are regulated both positively and negatively by the interactions of numerous signaling molecules. Mast cells that are thus activated release preformed granules which contain biogenic amines (especially histamines) and proteoglycans (especially heparin). The activation of phospholipase A2 causes the release of membrane lipids followed by development of lipid mediators such as leukotrienes (LTC4, LTD4 and LTE4) and prostaglandins (especially PDG2). There is also secretion of cytokines, the most important of which are TNF-alpha, IL-4 and IL-5. These mediators and cytokines contribute to inflammatory responses." @default.
- NCIT_C91476 normalizedInformationContent "68.718108343865637" @default.
- NCIT_C91476 referenceCount "113" @default.
- NCIT_C91476 hasExactSynonym "Fc Epsilon Receptor I Signaling Pathway KEGG" @default.
- NCIT_C91476 hasExactSynonym "Fc epsilon RI signaling pathway" @default.
- NCIT_C91476 type Class @default.
- NCIT_C91476 isDefinedBy ncit.owl @default.
- NCIT_C91476 label "Fc Epsilon Receptor I Signaling Pathway KEGG" @default.
- NCIT_C91476 subClassOf NCIT_C19779 @default.
- NCIT_C91476 subClassOf NCIT_C20633 @default.
- NCIT_C91476 subClassOf NCIT_C39698 @default.
- NCIT_C91476 subClassOf NCIT_C91476 @default.