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- NCIT_C91490 NCIT_NHC0 "C91490" @default.
- NCIT_C91490 NCIT_P106 "Functional Concept" @default.
- NCIT_C91490 NCIT_P108 "Type II Diabetes Mellitus Pathway" @default.
- NCIT_C91490 NCIT_P207 "C2984301" @default.
- NCIT_C91490 NCIT_P215 "hsa04930" @default.
- NCIT_C91490 NCIT_P325 "Insulin resistance is strongly associated with type II diabetes. "Diabetogenic" factors including FFA, TNFalpha and cellular stress induce insulin resistance through inhibition of IRS1 functions. Serine/threonine phosphorylation, interaction with SOCS, regulation of the expression, modification of the cellular localization, and degradation represent the molecular mechanisms stimulated by them. Various kinases (ERK, JNK, IKKbeta, PKCzeta, PKCtheta and mTOR) are involved in this process." @default.
- NCIT_C91490 normalizedInformationContent "71.342835337899871" @default.
- NCIT_C91490 referenceCount "76" @default.
- NCIT_C91490 hasExactSynonym "Type II Diabetes Mellitus Pathway" @default.
- NCIT_C91490 hasExactSynonym "Type II diabetes mellitus" @default.
- NCIT_C91490 type Class @default.
- NCIT_C91490 isDefinedBy ncit.owl @default.
- NCIT_C91490 label "Type II Diabetes Mellitus Pathway" @default.
- NCIT_C91490 subClassOf NCIT_C20633 @default.
- NCIT_C91490 subClassOf NCIT_C39701 @default.
- NCIT_C91490 subClassOf NCIT_C91490 @default.