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- NCIT_C91493 NCIT_NHC0 "C91493" @default.
- NCIT_C91493 NCIT_P106 "Functional Concept" @default.
- NCIT_C91493 NCIT_P108 "Collecting Duct Acid Secretion Pathway" @default.
- NCIT_C91493 NCIT_P207 "C2984304" @default.
- NCIT_C91493 NCIT_P215 "hsa04966" @default.
- NCIT_C91493 NCIT_P325 "One of the important roles of the collecting duct segment of the kidney nephron is acid secretion. As daily food intake loads acid into the body, urinary acid excretion is essential, and urine pH can drop as low as 4.5. The alpha-intercalated cell of collecting duct is the main responsible for hydrogen secretion into the urine. The carbon dioxide, which is generated in the cells and enters from the blood, is changed to carbonic acid. This carbonic acid is divided into hydrogen ion and bicarbonate ion. Intracellular CA II catalyses the formation of these ions. The hydrogen ion is secreted into the lumen by the luminal H(+)-ATPase. The bicarbonate ion is transported to the blood side by the anion exchanger type 1. Hydrogen ion in the lumen is trapped by urinary buffers. These include ammonium and phosphate." @default.
- NCIT_C91493 normalizedInformationContent "83.027314241919257" @default.
- NCIT_C91493 referenceCount "13" @default.
- NCIT_C91493 hasExactSynonym "Collecting Duct Acid Secretion Pathway" @default.
- NCIT_C91493 hasExactSynonym "Collecting duct acid secretion" @default.
- NCIT_C91493 type Class @default.
- NCIT_C91493 isDefinedBy ncit.owl @default.
- NCIT_C91493 label "Collecting Duct Acid Secretion Pathway" @default.
- NCIT_C91493 subClassOf NCIT_C19779 @default.
- NCIT_C91493 subClassOf NCIT_C20633 @default.
- NCIT_C91493 subClassOf NCIT_C91493 @default.
- NCIT_C91493 subClassOf NCIT_C91822 @default.