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- NCIT_C91736 IAO_0000115 "A liposomal formulation containing the antisense oligodeoxynucleotide (ODN) growth factor receptor-bound protein 2 (Grb2), with potential antineoplastic activity. Upon administration, liposome-incorporated Grb2 antisense oligodeoxynucleotide binds directly to and blocks Grb2 mRNA, thereby preventing Grb2 protein synthesis, leading to inhibition of cell proliferation of cancer cells overexpressing Grb2. Grb2, an adaptor protein involved in growth signaling pathways, is upregulated in certain tumor cells." @default.
- NCIT_C91736 NCIT_A32 NCIT_C1909 @default.
- NCIT_C91736 NCIT_A7 NCIT_C26222 @default.
- NCIT_C91736 NCIT_NHC0 "C91736" @default.
- NCIT_C91736 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C91736 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C91736 NCIT_P107 "Liposome-Incorporated Grb2 Antisense Oligodeoxynucleotide" @default.
- NCIT_C91736 NCIT_P108 "Prexigebersen" @default.
- NCIT_C91736 NCIT_P208 "CL421657" @default.
- NCIT_C91736 NCIT_P210 "202484-91-1" @default.
- NCIT_C91736 NCIT_P319 "8W1O4Y961B" @default.
- NCIT_C91736 NCIT_P322 "CTRP" @default.
- NCIT_C91736 NCIT_P322 "FDA" @default.
- NCIT_C91736 NCIT_P322 "GDC" @default.
- NCIT_C91736 NCIT_P329 "681815" @default.
- NCIT_C91736 NCIT_P330 "681815" @default.
- NCIT_C91736 NCIT_P375 "Prexigebersen" @default.
- NCIT_C91736 NCIT_P399 "681815" @default.
- NCIT_C91736 normalizedInformationContent "100" @default.
- NCIT_C91736 referenceCount "1" @default.
- NCIT_C91736 hasExactSynonym "BP-100-1.01" @default.
- NCIT_C91736 hasExactSynonym "BP-1001" @default.
- NCIT_C91736 hasExactSynonym "BP1001" @default.
- NCIT_C91736 hasExactSynonym "Liposomal Grb2 AS ODN" @default.
- NCIT_C91736 hasExactSynonym "Liposome-Incorporated Grb2 Antisense Oligodeoxynucleotide" @default.
- NCIT_C91736 hasExactSynonym "PREXIGEBERSEN" @default.
- NCIT_C91736 hasExactSynonym "Prexigebersen" @default.
- NCIT_C91736 inSubset NCIT_C116977 @default.
- NCIT_C91736 inSubset NCIT_C116978 @default.
- NCIT_C91736 inSubset NCIT_C128784 @default.
- NCIT_C91736 inSubset NCIT_C157711 @default.
- NCIT_C91736 inSubset NCIT_C157712 @default.
- NCIT_C91736 inSubset NCIT_C176424 @default.
- NCIT_C91736 inSubset NCIT_C177537 @default.
- NCIT_C91736 inSubset NCIT_C63923 @default.
- NCIT_C91736 type Class @default.
- NCIT_C91736 isDefinedBy ncit.owl @default.
- NCIT_C91736 label "Prexigebersen" @default.
- NCIT_C91736 subClassOf NCIT_C1291 @default.
- NCIT_C91736 subClassOf NCIT_C1908 @default.
- NCIT_C91736 subClassOf NCIT_C1909 @default.
- NCIT_C91736 subClassOf NCIT_C1962 @default.
- NCIT_C91736 subClassOf NCIT_C307 @default.
- NCIT_C91736 subClassOf NCIT_C91736 @default.