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- NCIT_C918 IAO_0000115 "An alkylating derivative of the pyrimidine nucleobase uracil that is bound to nitrogen mustard, with antineoplastic activity. Uramustine alkylates and damages DNA by binding to the guanine and cytosine moieties of DNA. This leads to cross-linking of DNA, which inhibits DNA synthesis and promotes cell death in rapidly metabolizing cells, such as cancer cells." @default.
- NCIT_C918 NCIT_NHC0 "C918" @default.
- NCIT_C918 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C918 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C918 NCIT_P108 "Uracil Mustard" @default.
- NCIT_C918 NCIT_P175 "34462" @default.
- NCIT_C918 NCIT_P207 "C0041920" @default.
- NCIT_C918 NCIT_P210 "66-75-1" @default.
- NCIT_C918 NCIT_P319 "W7KQ46GJ8U" @default.
- NCIT_C918 NCIT_P322 "FDA" @default.
- NCIT_C918 NCIT_P350 "C8H11Cl2N3O2" @default.
- NCIT_C918 NCIT_P366 "Uracil_Mustard" @default.
- NCIT_C918 NCIT_P368 "CHEBI:9884" @default.
- NCIT_C918 normalizedInformationContent "100" @default.
- NCIT_C918 referenceCount "1" @default.
- NCIT_C918 hasExactSynonym "5-(bis-(2-Chloroethyl) Amino) Uracil" @default.
- NCIT_C918 hasExactSynonym "5-[Bis(2-chloroethyl)amino]uracil" @default.
- NCIT_C918 hasExactSynonym "U 8344" @default.
- NCIT_C918 hasExactSynonym "U-8344" @default.
- NCIT_C918 hasExactSynonym "URACIL MUSTARD" @default.
- NCIT_C918 hasExactSynonym "Uracil Mustard" @default.
- NCIT_C918 hasExactSynonym "Uramustine" @default.
- NCIT_C918 inSubset NCIT_C63923 @default.
- NCIT_C918 type Class @default.
- NCIT_C918 isDefinedBy ncit.owl @default.
- NCIT_C918 label "Uracil Mustard" @default.
- NCIT_C918 subClassOf NCIT_C1590 @default.
- NCIT_C918 subClassOf NCIT_C186664 @default.
- NCIT_C918 subClassOf NCIT_C1908 @default.
- NCIT_C918 subClassOf NCIT_C1909 @default.
- NCIT_C918 subClassOf NCIT_C2114 @default.
- NCIT_C918 subClassOf NCIT_C274 @default.
- NCIT_C918 subClassOf NCIT_C2842 @default.
- NCIT_C918 subClassOf NCIT_C697 @default.
- NCIT_C918 subClassOf NCIT_C918 @default.