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- NCIT_C91811 NCIT_NHC0 "C91811" @default.
- NCIT_C91811 NCIT_P106 "Functional Concept" @default.
- NCIT_C91811 NCIT_P108 "Gastric Acid Secretion Pathway" @default.
- NCIT_C91811 NCIT_P207 "C2984576" @default.
- NCIT_C91811 NCIT_P215 "hsa04971" @default.
- NCIT_C91811 NCIT_P325 "Gastric acid is a key factor in normal upper gastrointestinal functions, including protein digestion and calcium and iron absorption, as well as providing some protection against bacterial infections. The principal stimulants of acid secretion at the level of the parietal cell are histamine (paracrine), gastrin (hormonal), and acetylcholine (ACh; neurocrine). Stimulation of acid secretion typically involves an initial elevation of intracellular calcium and cAMP, followed by activation of protein kinase cascades, which trigger the translocation of the proton pump, H+, K+-ATPase, from cytoplasmic tubulovesicles to the apical plasma membrane and H+ secretion into the stomach lumen." @default.
- NCIT_C91811 normalizedInformationContent "73.018273635347086" @default.
- NCIT_C91811 referenceCount "59" @default.
- NCIT_C91811 hasExactSynonym "Gastric Acid Secretion Pathway" @default.
- NCIT_C91811 hasExactSynonym "Gastric acid secretion" @default.
- NCIT_C91811 type Class @default.
- NCIT_C91811 isDefinedBy ncit.owl @default.
- NCIT_C91811 label "Gastric Acid Secretion Pathway" @default.
- NCIT_C91811 subClassOf NCIT_C19779 @default.
- NCIT_C91811 subClassOf NCIT_C20633 @default.
- NCIT_C91811 subClassOf NCIT_C91811 @default.
- NCIT_C91811 subClassOf NCIT_C91822 @default.