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- NCIT_C925 IAO_0000115 "A branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site different from that of penicillins and cephalosporins, vancomycin binds tightly to the D-alanyl-D-alanine portion of cell wall precursors, thereby interfering with bacterial cell wall synthesis. This leads to activation of bacterial autolysins that destroy the cell wall by lysis. Vancomycin may also alter the permeability of bacterial cytoplasmic membranes and may selectively inhibit RNA synthesis." @default.
- NCIT_C925 NCIT_A5 NCIT_C65207 @default.
- NCIT_C925 NCIT_NHC0 "C925" @default.
- NCIT_C925 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C925 NCIT_P106 "Antibiotic" @default.
- NCIT_C925 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C925 NCIT_P107 "Vancomycin" @default.
- NCIT_C925 NCIT_P108 "Vancomycin" @default.
- NCIT_C925 NCIT_P207 "C0042313" @default.
- NCIT_C925 NCIT_P210 "1404-90-6" @default.
- NCIT_C925 NCIT_P319 "6Q205EH1VU" @default.
- NCIT_C925 NCIT_P322 "CTRP" @default.
- NCIT_C925 NCIT_P322 "FDA" @default.
- NCIT_C925 NCIT_P325 "An antibiotic drug used to fight resistant bacterial infections." @default.
- NCIT_C925 NCIT_P329 "39731" @default.
- NCIT_C925 NCIT_P330 "39731" @default.
- NCIT_C925 NCIT_P350 "C66H75Cl2N9O24" @default.
- NCIT_C925 NCIT_P366 "Vancomycin" @default.
- NCIT_C925 NCIT_P368 "CHEBI:28001" @default.
- NCIT_C925 NCIT_P399 "39731" @default.
- NCIT_C925 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C925 referenceCount "3" @default.
- NCIT_C925 hasExactSynonym "VANCOMYCIN" @default.
- NCIT_C925 hasExactSynonym "Vancomycin" @default.
- NCIT_C925 hasExactSynonym "vancomycin" @default.
- NCIT_C925 inSubset NCIT_C116977 @default.
- NCIT_C925 inSubset NCIT_C116978 @default.
- NCIT_C925 inSubset NCIT_C176424 @default.
- NCIT_C925 inSubset NCIT_C63923 @default.
- NCIT_C925 type Class @default.
- NCIT_C925 isDefinedBy ncit.owl @default.
- NCIT_C925 label "Vancomycin" @default.
- NCIT_C925 subClassOf NCIT_C1908 @default.
- NCIT_C925 subClassOf NCIT_C1909 @default.
- NCIT_C925 subClassOf NCIT_C254 @default.
- NCIT_C925 subClassOf NCIT_C258 @default.
- NCIT_C925 subClassOf NCIT_C61101 @default.
- NCIT_C925 subClassOf NCIT_C925 @default.