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- NCIT_C92572 IAO_0000115 "An orally active and small molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor Debio 0932 specifically blocks Hsp90, thereby inhibiting its chaperone function and promoting the degradation of its client proteins, many of which are oncogenic signaling proteins involved in tumor cell proliferation and survival. This may lead to an inhibition of tumor cell proliferation. Hsp90, a chaperone protein upregulated in a variety of tumor cells, regulates the folding, stabilization and degradation of many oncogenic signaling proteins." @default.
- NCIT_C92572 NCIT_A32 NCIT_C1909 @default.
- NCIT_C92572 NCIT_NHC0 "C92572" @default.
- NCIT_C92572 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C92572 NCIT_P108 "Hsp90 Inhibitor Debio 0932" @default.
- NCIT_C92572 NCIT_P207 "C2742735" @default.
- NCIT_C92572 NCIT_P210 "1061318-81-7" @default.
- NCIT_C92572 NCIT_P319 "0V278OKN9G" @default.
- NCIT_C92572 NCIT_P322 "FDA" @default.
- NCIT_C92572 NCIT_P322 "GDC" @default.
- NCIT_C92572 NCIT_P329 "682685" @default.
- NCIT_C92572 NCIT_P330 "682685" @default.
- NCIT_C92572 NCIT_P375 "Hsp90 Inhibitor Debio 0932" @default.
- NCIT_C92572 NCIT_P399 "682685" @default.
- NCIT_C92572 NCIT_R125 NCIT_C17828 @default.
- NCIT_C92572 NCIT_R125 NCIT_C20150 @default.
- NCIT_C92572 NCIT_R125 NCIT_C20480 @default.
- NCIT_C92572 NCIT_R125 NCIT_C40715 @default.
- NCIT_C92572 NCIT_R125 NCIT_C41515 @default.
- NCIT_C92572 NCIT_R125 NCIT_C51037 @default.
- NCIT_C92572 normalizedInformationContent "100" @default.
- NCIT_C92572 referenceCount "1" @default.
- NCIT_C92572 hasExactSynonym "CUDC-305" @default.
- NCIT_C92572 hasExactSynonym "Debio 0932" @default.
- NCIT_C92572 hasExactSynonym "Debio-0932" @default.
- NCIT_C92572 hasExactSynonym "Hsp90 Inhibitor Debio 0932" @default.
- NCIT_C92572 inSubset NCIT_C128784 @default.
- NCIT_C92572 inSubset NCIT_C157711 @default.
- NCIT_C92572 inSubset NCIT_C157712 @default.
- NCIT_C92572 inSubset NCIT_C176424 @default.
- NCIT_C92572 inSubset NCIT_C177537 @default.
- NCIT_C92572 inSubset NCIT_C63923 @default.
- NCIT_C92572 type Class @default.
- NCIT_C92572 isDefinedBy ncit.owl @default.
- NCIT_C92572 label "Hsp90 Inhibitor Debio 0932" @default.
- NCIT_C92572 subClassOf NCIT_C129824 @default.
- NCIT_C92572 subClassOf NCIT_C156880 @default.
- NCIT_C92572 subClassOf NCIT_C1908 @default.
- NCIT_C92572 subClassOf NCIT_C1909 @default.
- NCIT_C92572 subClassOf NCIT_C2189 @default.
- NCIT_C92572 subClassOf NCIT_C274 @default.
- NCIT_C92572 subClassOf NCIT_C74526 @default.
- NCIT_C92572 subClassOf NCIT_C92572 @default.