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- NCIT_C930 IAO_0000115 "A natural alkaloid isolated from the plant Vinca rosea Linn. Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the M phase of the cell cycle. This agent may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin-dependent Ca++ -transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis. (NCI04)" @default.
- NCIT_C930 NCIT_A32 NCIT_C1909 @default.
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- NCIT_C930 NCIT_A7 NCIT_C129655 @default.
- NCIT_C930 NCIT_NHC0 "C930" @default.
- NCIT_C930 NCIT_P106 "Organic Chemical" @default.
- NCIT_C930 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C930 NCIT_P107 "Vinblastine" @default.
- NCIT_C930 NCIT_P108 "Vinblastine" @default.
- NCIT_C930 NCIT_P175 "90636" @default.
- NCIT_C930 NCIT_P207 "C0042670" @default.
- NCIT_C930 NCIT_P210 "865-21-4" @default.
- NCIT_C930 NCIT_P302 "Bladder cancer; Breast cancer; Choriocarcinoma; Germ cell tumors; Idiopathic thrombocytopenic purpura; Kaposi sarcoma; Letterer-Siwe disease; Various Lymphomas; Melanoma; Mycosis fungoides; Prostate cancer; Testicular cancer" @default.
- NCIT_C930 NCIT_P319 "5V9KLZ54CY" @default.
- NCIT_C930 NCIT_P322 "CTRP" @default.
- NCIT_C930 NCIT_P322 "FDA" @default.
- NCIT_C930 NCIT_P322 "GDC" @default.
- NCIT_C930 NCIT_P322 "PCDC" @default.
- NCIT_C930 NCIT_P325 "The active ingredient in a drug used together with other drugs to treat several types of cancer, including advanced Hodgkin lymphoma and advanced testicular germinal-cell cancers. It is also being studied in the treatment of other types of cancer. Vinblastine comes from the periwinkle plant Vinca rosea Linn. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of vinca alkaloid and a type of antimitotic agent." @default.
- NCIT_C930 NCIT_P329 "42951" @default.
- NCIT_C930 NCIT_P330 "42951" @default.
- NCIT_C930 NCIT_P350 "C46H58N4O9" @default.
- NCIT_C930 NCIT_P366 "Vinblastine" @default.
- NCIT_C930 NCIT_P368 "CHEBI:27375" @default.
- NCIT_C930 NCIT_P375 "Vinblastine" @default.
- NCIT_C930 NCIT_P399 "42951" @default.
- NCIT_C930 NCIT_R122 NCIT_C16484 @default.
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- NCIT_C930 NCIT_R124 NCIT_C40798 @default.
- NCIT_C930 normalizedInformationContent "67.63976693763766" @default.
- NCIT_C930 referenceCount "133" @default.
- NCIT_C930 hasExactSynonym "VINBLASTINE" @default.
- NCIT_C930 hasExactSynonym "VLB" @default.
- NCIT_C930 hasExactSynonym "Vinblastine" @default.
- NCIT_C930 hasExactSynonym "Vincaleucoblastine" @default.
- NCIT_C930 hasExactSynonym "vinblastine" @default.
- NCIT_C930 inSubset NCIT_C116977 @default.
- NCIT_C930 inSubset NCIT_C116978 @default.
- NCIT_C930 inSubset NCIT_C128784 @default.
- NCIT_C930 inSubset NCIT_C157711 @default.
- NCIT_C930 inSubset NCIT_C157712 @default.
- NCIT_C930 inSubset NCIT_C176424 @default.
- NCIT_C930 inSubset NCIT_C177383 @default.
- NCIT_C930 inSubset NCIT_C177406 @default.
- NCIT_C930 inSubset NCIT_C177537 @default.
- NCIT_C930 inSubset NCIT_C186327 @default.
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- NCIT_C930 inSubset NCIT_C63923 @default.
- NCIT_C930 type Class @default.
- NCIT_C930 isDefinedBy ncit.owl @default.
- NCIT_C930 label "Vinblastine" @default.
- NCIT_C930 subClassOf B2de596bf74b22ddd342fc9942aca12f8 @default.
- NCIT_C930 subClassOf B63d22eb109d5797ad181e6894c7ed14b @default.
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- NCIT_C930 subClassOf NCIT_C718 @default.
- NCIT_C930 subClassOf NCIT_C930 @default.
- NCIT_C930 subClassOf NCIT_C932 @default.