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- NCIT_C93170 IAO_0000115 "Any monoclonal antibody directed against the human tyrosine kinase vascular endothelial growth factor receptor (VEGFR), with potential anti-angiogenic and antineoplastic activities. An anti-VEGFR monoclonal antibody binds to and inhibits the activity of VEGFR, which may prevent the activation of downstream signaling pathways and tumor angiogenesis; the subsequent reduction in tumor nutrient supply may inhibit tumor cell proliferation. The expression of the pro-angiogenic growth factor VEGF is associated with tumor angiogenesis and tumor cell proliferation and invasion." @default.
- NCIT_C93170 NCIT_NHC0 "C93170" @default.
- NCIT_C93170 NCIT_P106 "Classification" @default.
- NCIT_C93170 NCIT_P108 "Anti-VEGFR Monoclonal Antibody" @default.
- NCIT_C93170 NCIT_P207 "C2985475" @default.
- NCIT_C93170 NCIT_P325 "A monoclonal antibody being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Anti-VEGFR monoclonal antibodies bind to receptors for vascular endothelial growth factor (VEGF) and keeps VEGF from binding to them. This may stop the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent." @default.
- NCIT_C93170 NCIT_R124 NCIT_C17710 @default.
- NCIT_C93170 NCIT_R124 NCIT_C17828 @default.
- NCIT_C93170 NCIT_R124 NCIT_C18219 @default.
- NCIT_C93170 NCIT_R124 NCIT_C19986 @default.
- NCIT_C93170 NCIT_R124 NCIT_C40474 @default.
- NCIT_C93170 normalizedInformationContent "82.080392758357064" @default.
- NCIT_C93170 referenceCount "15" @default.
- NCIT_C93170 hasExactSynonym "Anti-VEGFR Monoclonal Antibody" @default.
- NCIT_C93170 hasExactSynonym "anti-VEGFR monoclonal antibody" @default.
- NCIT_C93170 type Class @default.
- NCIT_C93170 isDefinedBy ncit.owl @default.
- NCIT_C93170 label "Anti-VEGFR Monoclonal Antibody" @default.
- NCIT_C93170 subClassOf NCIT_C163758 @default.
- NCIT_C93170 subClassOf NCIT_C163953 @default.
- NCIT_C93170 subClassOf NCIT_C1742 @default.
- NCIT_C93170 subClassOf NCIT_C1908 @default.
- NCIT_C93170 subClassOf NCIT_C1909 @default.
- NCIT_C93170 subClassOf NCIT_C20401 @default.
- NCIT_C93170 subClassOf NCIT_C274 @default.
- NCIT_C93170 subClassOf NCIT_C307 @default.
- NCIT_C93170 subClassOf NCIT_C308 @default.
- NCIT_C93170 subClassOf NCIT_C93170 @default.