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- NCIT_C94217 IAO_0000115 "An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. Anti-CTLA4 MoAb RNA-transfected autologous DC vaccine is prepared by transfecting DCs with RNAs encoding humanized heavy and light chains of the anti-CTLA4 (cytotoxic T-Lymphocyte-Associated Antigen 4); expression of anti-CTLA4 blocks the inhibitory effect of CTLA4 on the activation of T-lymphocytes. Co-vaccination of this vaccine with melanoma antigen specific vaccine may eliminate the adverse effects associated with systemic administration of immune modulators, while also enhancing vaccine-induced immune responses." @default.
- NCIT_C94217 NCIT_A7 NCIT_C17489 @default.
- NCIT_C94217 NCIT_NHC0 "C94217" @default.
- NCIT_C94217 NCIT_P106 "Cell" @default.
- NCIT_C94217 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C94217 NCIT_P107 "Anti-CTLA4 MoAb RNA-transfected Autologous Dendritic Cell Vaccine" @default.
- NCIT_C94217 NCIT_P108 "Anti-CTLA4 MoAb RNA-transfected Autologous Dendritic Cell Vaccine" @default.
- NCIT_C94217 NCIT_P207 "C2986402" @default.
- NCIT_C94217 NCIT_P322 "CTRP" @default.
- NCIT_C94217 NCIT_P329 "687564" @default.
- NCIT_C94217 NCIT_P330 "687564" @default.
- NCIT_C94217 NCIT_P399 "687564" @default.
- NCIT_C94217 normalizedInformationContent "100" @default.
- NCIT_C94217 referenceCount "1" @default.
- NCIT_C94217 hasExactSynonym "Anti-CTLA4 MoAb RNA-transfected Autologous Dendritic Cell Vaccine" @default.
- NCIT_C94217 hasExactSynonym "anti-CTLA-4 mAb Heavy and Light Chain RNA-transfected Autologous DC" @default.
- NCIT_C94217 hasExactSynonym "antiCTLA4 RNA DC" @default.
- NCIT_C94217 inSubset NCIT_C116977 @default.
- NCIT_C94217 inSubset NCIT_C116978 @default.
- NCIT_C94217 inSubset NCIT_C128784 @default.
- NCIT_C94217 inSubset NCIT_C176424 @default.
- NCIT_C94217 type Class @default.
- NCIT_C94217 isDefinedBy ncit.owl @default.
- NCIT_C94217 label "Anti-CTLA4 MoAb RNA-transfected Autologous Dendritic Cell Vaccine" @default.
- NCIT_C94217 subClassOf NCIT_C129820 @default.
- NCIT_C94217 subClassOf NCIT_C1663 @default.
- NCIT_C94217 subClassOf NCIT_C172787 @default.
- NCIT_C94217 subClassOf NCIT_C181141 @default.
- NCIT_C94217 subClassOf NCIT_C1908 @default.
- NCIT_C94217 subClassOf NCIT_C1909 @default.
- NCIT_C94217 subClassOf NCIT_C274 @default.
- NCIT_C94217 subClassOf NCIT_C28308 @default.
- NCIT_C94217 subClassOf NCIT_C28310 @default.
- NCIT_C94217 subClassOf NCIT_C307 @default.
- NCIT_C94217 subClassOf NCIT_C308 @default.
- NCIT_C94217 subClassOf NCIT_C923 @default.
- NCIT_C94217 subClassOf NCIT_C94217 @default.