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- NCIT_C946 IAO_0000115 "The sodium salt of a semisynthetic heparin-like glucosaminoglycan. Although its mechanism of action is unknown, pentosan polysulfate may act as a buffer to control cell permeability by preventing irritating solutes from reaching cells coated with it. Administered orally, excreted pentosan polysulfate adheres to the urinary bladder wall, preventing irritants from entering bladder cells and the development or progression of interstitial cystitis (IC), a complication of some chemotherapies. This agent also exhibits anticoagulant and fibrinolytic properties. In addition, pentosan polysulfate may block endothelial P-selectin and increase microvascular blood flow in sickle cell disease." @default.
- NCIT_C946 NCIT_A6 NCIT_C1755 @default.
- NCIT_C946 NCIT_NHC0 "C946" @default.
- NCIT_C946 NCIT_P106 "Organic Chemical" @default.
- NCIT_C946 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C946 NCIT_P107 "Pentosan Polysulfate Sodium" @default.
- NCIT_C946 NCIT_P108 "Pentosan Polysulfate Sodium" @default.
- NCIT_C946 NCIT_P207 "C0524684" @default.
- NCIT_C946 NCIT_P210 "140207-93-8" @default.
- NCIT_C946 NCIT_P319 "914032762Y" @default.
- NCIT_C946 NCIT_P322 "CTRP" @default.
- NCIT_C946 NCIT_P322 "FDA" @default.
- NCIT_C946 NCIT_P329 "40350" @default.
- NCIT_C946 NCIT_P330 "40350" @default.
- NCIT_C946 NCIT_P350 "(C5H6Na2O10S2)n" @default.
- NCIT_C946 NCIT_P366 "Pentosan_Polysulfate_Sodium" @default.
- NCIT_C946 NCIT_P399 "40350" @default.
- NCIT_C946 normalizedInformationContent "100" @default.
- NCIT_C946 referenceCount "1" @default.
- NCIT_C946 hasExactSynonym "Cartrophen" @default.
- NCIT_C946 hasExactSynonym "Elmiron" @default.
- NCIT_C946 hasExactSynonym "Fibrase" @default.
- NCIT_C946 hasExactSynonym "Fibrezym" @default.
- NCIT_C946 hasExactSynonym "Fibrocid" @default.
- NCIT_C946 hasExactSynonym "HOE-BAY 946" @default.
- NCIT_C946 hasExactSynonym "Hemoclar" @default.
- NCIT_C946 hasExactSynonym "PENTOSAN POLYSULFATE SODIUM" @default.
- NCIT_C946 hasExactSynonym "Pentosan Polysulfate Sodium" @default.
- NCIT_C946 hasExactSynonym "Pentosan" @default.
- NCIT_C946 hasExactSynonym "Sodium Pentosan Polysulfate" @default.
- NCIT_C946 hasExactSynonym "Sodium Xylan Polysulfate" @default.
- NCIT_C946 hasExactSynonym "TRF 1101" @default.
- NCIT_C946 hasExactSynonym "TRF-1101" @default.
- NCIT_C946 hasExactSynonym "TRF1101" @default.
- NCIT_C946 hasExactSynonym "Tavan SP-54" @default.
- NCIT_C946 hasExactSynonym "Thrombocid" @default.
- NCIT_C946 inSubset NCIT_C116977 @default.
- NCIT_C946 inSubset NCIT_C116978 @default.
- NCIT_C946 inSubset NCIT_C176424 @default.
- NCIT_C946 inSubset NCIT_C63923 @default.
- NCIT_C946 type Class @default.
- NCIT_C946 isDefinedBy ncit.owl @default.
- NCIT_C946 label "Pentosan Polysulfate Sodium" @default.
- NCIT_C946 subClassOf NCIT_C1908 @default.
- NCIT_C946 subClassOf NCIT_C1909 @default.
- NCIT_C946 subClassOf NCIT_C263 @default.
- NCIT_C946 subClassOf NCIT_C78275 @default.
- NCIT_C946 subClassOf NCIT_C946 @default.