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- NCIT_C95114 IAO_0000115 "A protein complex that plays a role in the intramembrane cleavage of integral proteins such as Notch receptors and amyloid beta A4 protein." @default.
- NCIT_C95114 NCIT_NHC0 "C95114" @default.
- NCIT_C95114 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C95114 NCIT_P106 "Enzyme" @default.
- NCIT_C95114 NCIT_P108 "Gamma Secretase" @default.
- NCIT_C95114 NCIT_P207 "C0379528" @default.
- NCIT_C95114 NCIT_P98 "The components required for the enzymatic activity of gamma secretase are a homodimer of presenilin (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. The proteolytic activity appears to be mediated by presenilin, while the other proteins are required for both stabilization of the active form of presenilin and localization of the complex." @default.
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- NCIT_C95114 normalizedInformationContent "89.350088392419622" @default.
- NCIT_C95114 referenceCount "5" @default.
- NCIT_C95114 hasExactSynonym "Gamma Secretase" @default.
- NCIT_C95114 hasExactSynonym "Gamma-Secretase" @default.
- NCIT_C95114 type Class @default.
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- NCIT_C95114 label "Gamma Secretase" @default.
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