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- NCIT_C95214 IAO_0000115 "A highly modified, fourth generation linear decapeptide with gonadotropin-releasing hormone (GnRH or LHRH) antagonizing properties. Ozarelix competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with hormonally dependent disease states such as hormone-dependent prostate cancer." @default.
- NCIT_C95214 NCIT_A32 NCIT_C1909 @default.
- NCIT_C95214 NCIT_NHC0 "C95214" @default.
- NCIT_C95214 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C95214 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C95214 NCIT_P108 "Ozarelix" @default.
- NCIT_C95214 NCIT_P207 "C2987000" @default.
- NCIT_C95214 NCIT_P210 "295350-45-7" @default.
- NCIT_C95214 NCIT_P319 "Q1IF8M2YL3" @default.
- NCIT_C95214 NCIT_P322 "FDA" @default.
- NCIT_C95214 NCIT_P322 "GDC" @default.
- NCIT_C95214 NCIT_P329 "690937" @default.
- NCIT_C95214 NCIT_P330 "690937" @default.
- NCIT_C95214 NCIT_P375 "Ozarelix" @default.
- NCIT_C95214 NCIT_P399 "690937" @default.
- NCIT_C95214 normalizedInformationContent "100" @default.
- NCIT_C95214 referenceCount "1" @default.
- NCIT_C95214 hasExactSynonym "D 63153" @default.
- NCIT_C95214 hasExactSynonym "D-63 153" @default.
- NCIT_C95214 hasExactSynonym "D63 153" @default.
- NCIT_C95214 hasExactSynonym "D63153" @default.
- NCIT_C95214 hasExactSynonym "LHRH antagonist SPI-153" @default.
- NCIT_C95214 hasExactSynonym "OZARELIX" @default.
- NCIT_C95214 hasExactSynonym "Ozarelix" @default.
- NCIT_C95214 hasExactSynonym "SPI-153" @default.
- NCIT_C95214 inSubset NCIT_C128784 @default.
- NCIT_C95214 inSubset NCIT_C157711 @default.
- NCIT_C95214 inSubset NCIT_C157712 @default.
- NCIT_C95214 inSubset NCIT_C176424 @default.
- NCIT_C95214 inSubset NCIT_C177537 @default.
- NCIT_C95214 inSubset NCIT_C63923 @default.
- NCIT_C95214 type Class @default.
- NCIT_C95214 isDefinedBy ncit.owl @default.
- NCIT_C95214 label "Ozarelix" @default.
- NCIT_C95214 subClassOf NCIT_C147908 @default.
- NCIT_C95214 subClassOf NCIT_C1908 @default.
- NCIT_C95214 subClassOf NCIT_C1909 @default.
- NCIT_C95214 subClassOf NCIT_C2092 @default.
- NCIT_C95214 subClassOf NCIT_C547 @default.
- NCIT_C95214 subClassOf NCIT_C95214 @default.