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- NCIT_C95224 IAO_0000115 "The difumarate salt of saracatinib, an orally available 5-, 7-substituted anilinoquinazoline with anti-invasive and anti-tumor activities. Saracatinib is a dual-specific inhibitor of Src and Abl, protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. This agent binds to and inhibits these tyrosine kinases and affects cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival. Specifically, Saracatinib inhibits Src kinase-mediated osteoclast bone resorption." @default.
- NCIT_C95224 NCIT_A32 NCIT_C1909 @default.
- NCIT_C95224 NCIT_A6 NCIT_C48378 @default.
- NCIT_C95224 NCIT_NHC0 "C95224" @default.
- NCIT_C95224 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C95224 NCIT_P108 "Saracatinib Difumarate" @default.
- NCIT_C95224 NCIT_P207 "C2987006" @default.
- NCIT_C95224 NCIT_P210 "893428-72-3" @default.
- NCIT_C95224 NCIT_P319 "8R1DYT4EAW" @default.
- NCIT_C95224 NCIT_P322 "FDA" @default.
- NCIT_C95224 NCIT_P322 "GDC" @default.
- NCIT_C95224 NCIT_P350 "C27H32ClN5O5.2C4H4O4" @default.
- NCIT_C95224 NCIT_P375 "Saracatinib Difumarate" @default.
- NCIT_C95224 NCIT_R124 NCIT_C17710 @default.
- NCIT_C95224 NCIT_R124 NCIT_C17828 @default.
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- NCIT_C95224 NCIT_R125 NCIT_C28486 @default.
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- NCIT_C95224 NCIT_R146 NCIT_C16554 @default.
- NCIT_C95224 NCIT_R146 NCIT_C16984 @default.
- NCIT_C95224 NCIT_R146 NCIT_C17018 @default.
- NCIT_C95224 NCIT_R146 NCIT_C17020 @default.
- NCIT_C95224 NCIT_R146 NCIT_C17021 @default.
- NCIT_C95224 NCIT_R146 NCIT_C17210 @default.
- NCIT_C95224 NCIT_R146 NCIT_C17893 @default.
- NCIT_C95224 NCIT_R146 NCIT_C20027 @default.
- NCIT_C95224 NCIT_R146 NCIT_C26548 @default.
- NCIT_C95224 normalizedInformationContent "100" @default.
- NCIT_C95224 referenceCount "1" @default.
- NCIT_C95224 hasExactSynonym "4-Quinazolinamine, N-(5-Chloro-1,3-Benzodioxol-4-yl)-7-(2-(4-Methyl-1-Piperazinyl)Ethoxy)-5-((Tetrahydro-2H-Pyran-4-yl)Oxy)-, (2e)-2-Butenedioate (1:2)" @default.
- NCIT_C95224 hasExactSynonym "AZD-0530 Difumarate" @default.
- NCIT_C95224 hasExactSynonym "AZD0530 Difumarate" @default.
- NCIT_C95224 hasExactSynonym "N-(5-Chloro-1,3-Benzodioxol-4-yl)-7-(2-(4-Methylpiperazin-1-yl)Ethoxy)-5-(Tetrahydro-2H-Pyran-4-yloxy)Quinazolin-4-Amine Di((2e)-but-2-Enedioate)" @default.
- NCIT_C95224 hasExactSynonym "SARACATINIB DIFUMARATE" @default.
- NCIT_C95224 hasExactSynonym "Saracatinib Difumarate" @default.
- NCIT_C95224 inSubset NCIT_C128784 @default.
- NCIT_C95224 inSubset NCIT_C157711 @default.
- NCIT_C95224 inSubset NCIT_C157712 @default.
- NCIT_C95224 inSubset NCIT_C177537 @default.
- NCIT_C95224 inSubset NCIT_C63923 @default.
- NCIT_C95224 type Class @default.
- NCIT_C95224 isDefinedBy ncit.owl @default.
- NCIT_C95224 label "Saracatinib Difumarate" @default.
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- NCIT_C95224 subClassOf NCIT_C1967 @default.
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