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- NCIT_C95284 IAO_0000115 "The hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activities. Tropisetron competitively binds to and blocks the action of serotonin at 5HT3 receptors peripherally on vagus nerve terminals located in the gastrointestinal (GI) tract as well as centrally in the chemoreceptor trigger zone (CTZ) of the area postrema of the central nervous system (CNS). This results in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting." @default.
- NCIT_C95284 NCIT_A6 NCIT_C1131 @default.
- NCIT_C95284 NCIT_NHC0 "C95284" @default.
- NCIT_C95284 NCIT_P106 "Organic Chemical" @default.
- NCIT_C95284 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C95284 NCIT_P108 "Tropisetron Hydrochloride" @default.
- NCIT_C95284 NCIT_P207 "C0771211" @default.
- NCIT_C95284 NCIT_P210 "105826-92-4" @default.
- NCIT_C95284 NCIT_P319 "A19338Q2YO" @default.
- NCIT_C95284 NCIT_P322 "FDA" @default.
- NCIT_C95284 NCIT_P329 "776838" @default.
- NCIT_C95284 NCIT_P330 "776838" @default.
- NCIT_C95284 NCIT_P350 "C17H20N2O2.HCl" @default.
- NCIT_C95284 NCIT_P399 "776838" @default.
- NCIT_C95284 normalizedInformationContent "100" @default.
- NCIT_C95284 referenceCount "1" @default.
- NCIT_C95284 hasExactSynonym "1H-Indole-3-Carboxylic Acid, (3-endo)-8-Methyl-8-Azabicyclo(3.2.1)Oct-3-yl Ester, Monohydrochloride" @default.
- NCIT_C95284 hasExactSynonym "1alpha-H,5alpha-H-tropan-3alpha-yl Indole-3-Carboxylate Hydrochloride" @default.
- NCIT_C95284 hasExactSynonym "Novaban" @default.
- NCIT_C95284 hasExactSynonym "SDZ-ICS 930" @default.
- NCIT_C95284 hasExactSynonym "TROPISETRON HYDROCHLORIDE" @default.
- NCIT_C95284 hasExactSynonym "Tropisetron Hydrochloride" @default.
- NCIT_C95284 inSubset NCIT_C176424 @default.
- NCIT_C95284 inSubset NCIT_C63923 @default.
- NCIT_C95284 type Class @default.
- NCIT_C95284 isDefinedBy ncit.owl @default.
- NCIT_C95284 label "Tropisetron Hydrochloride" @default.
- NCIT_C95284 subClassOf NCIT_C1908 @default.
- NCIT_C95284 subClassOf NCIT_C1909 @default.
- NCIT_C95284 subClassOf NCIT_C267 @default.
- NCIT_C95284 subClassOf NCIT_C66885 @default.
- NCIT_C95284 subClassOf NCIT_C78272 @default.
- NCIT_C95284 subClassOf NCIT_C94726 @default.
- NCIT_C95284 subClassOf NCIT_C95284 @default.