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- NCIT_C95732 IAO_0000115 "A humanized IgG4 monoclonal antibody directed against human hepatocyte growth factor receptor (HGFR or c-MET) with potential antineoplastic activity. Emibetuzumab binds to c-MET, thereby preventing the binding of HGF to its receptor c-Met and subsequent activation of the HGF/c-Met signaling pathway. This may result in cell death in c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays a key role in cancer cell growth, survival, angiogenesis, invasion, and metastasis." @default.
- NCIT_C95732 NCIT_A32 NCIT_C1909 @default.
- NCIT_C95732 NCIT_A7 NCIT_C18186 @default.
- NCIT_C95732 NCIT_NHC0 "C95732" @default.
- NCIT_C95732 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C95732 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C95732 NCIT_P107 "Emibetuzumab" @default.
- NCIT_C95732 NCIT_P108 "Emibetuzumab" @default.
- NCIT_C95732 NCIT_P207 "C2987383" @default.
- NCIT_C95732 NCIT_P210 "1365287-97-3" @default.
- NCIT_C95732 NCIT_P319 "MO4K3GDN1I" @default.
- NCIT_C95732 NCIT_P322 "CTRP" @default.
- NCIT_C95732 NCIT_P322 "FDA" @default.
- NCIT_C95732 NCIT_P322 "GDC" @default.
- NCIT_C95732 NCIT_P329 "694952" @default.
- NCIT_C95732 NCIT_P330 "694952" @default.
- NCIT_C95732 NCIT_P375 "Anti-c-MET Monoclonal Antibody LY2875358" @default.
- NCIT_C95732 NCIT_P375 "Emibetuzumab" @default.
- NCIT_C95732 NCIT_P399 "694952" @default.
- NCIT_C95732 NCIT_R124 NCIT_C17710 @default.
- NCIT_C95732 NCIT_R124 NCIT_C17828 @default.
- NCIT_C95732 NCIT_R124 NCIT_C18219 @default.
- NCIT_C95732 NCIT_R124 NCIT_C19986 @default.
- NCIT_C95732 NCIT_R124 NCIT_C40474 @default.
- NCIT_C95732 normalizedInformationContent "100" @default.
- NCIT_C95732 referenceCount "1" @default.
- NCIT_C95732 hasExactSynonym "Anti-c-MET Monoclonal Antibody LY2875358" @default.
- NCIT_C95732 hasExactSynonym "EMIBETUZUMAB" @default.
- NCIT_C95732 hasExactSynonym "Emibetuzumab" @default.
- NCIT_C95732 hasExactSynonym "LA-480" @default.
- NCIT_C95732 hasExactSynonym "LY2875358" @default.
- NCIT_C95732 inSubset NCIT_C116977 @default.
- NCIT_C95732 inSubset NCIT_C116978 @default.
- NCIT_C95732 inSubset NCIT_C128784 @default.
- NCIT_C95732 inSubset NCIT_C157711 @default.
- NCIT_C95732 inSubset NCIT_C157712 @default.
- NCIT_C95732 inSubset NCIT_C176424 @default.
- NCIT_C95732 inSubset NCIT_C177537 @default.
- NCIT_C95732 inSubset NCIT_C63923 @default.
- NCIT_C95732 type Class @default.
- NCIT_C95732 isDefinedBy ncit.owl @default.
- NCIT_C95732 label "Emibetuzumab" @default.
- NCIT_C95732 subClassOf NCIT_C129821 @default.
- NCIT_C95732 subClassOf NCIT_C129822 @default.
- NCIT_C95732 subClassOf NCIT_C163758 @default.
- NCIT_C95732 subClassOf NCIT_C164000 @default.
- NCIT_C95732 subClassOf NCIT_C164001 @default.
- NCIT_C95732 subClassOf NCIT_C1908 @default.
- NCIT_C95732 subClassOf NCIT_C1909 @default.
- NCIT_C95732 subClassOf NCIT_C20401 @default.
- NCIT_C95732 subClassOf NCIT_C274 @default.
- NCIT_C95732 subClassOf NCIT_C307 @default.
- NCIT_C95732 subClassOf NCIT_C308 @default.
- NCIT_C95732 subClassOf NCIT_C95732 @default.