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- NCIT_C96040 IAO_0000115 "An agonistic monoclonal antibody against receptor OX40 (CD134), with potential immunostimulatory activity. Mimicking the natural OX4 ligand (OX40L), anti-OX40 monoclonal antibody selectively binds to and activates the OX40 receptor. Receptor activation induces proliferation of memory and effector T lymphocytes. In the presence of tumor associated antigens (TAAs), this may promote an immune response against the TAA-expressing tumor cells. OX40, a cell surface glycoprotein and member of the tumor necrosis factor (TNF) receptor family, is expressed by CD4 T cells and provides a costimulatory signal for T cell activation." @default.
- NCIT_C96040 NCIT_NHC0 "C96040" @default.
- NCIT_C96040 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C96040 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C96040 NCIT_P108 "Anti-OX40 Monoclonal Antibody" @default.
- NCIT_C96040 NCIT_P208 "CL428374" @default.
- NCIT_C96040 NCIT_P329 "696645" @default.
- NCIT_C96040 NCIT_P330 "696645" @default.
- NCIT_C96040 NCIT_P399 "696645" @default.
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- NCIT_C96040 normalizedInformationContent "80.176753842542439" @default.
- NCIT_C96040 referenceCount "20" @default.
- NCIT_C96040 hasExactSynonym "Anti-OX40 Monoclonal Antibody" @default.
- NCIT_C96040 hasExactSynonym "anti-OX40 MoAb" @default.
- NCIT_C96040 inSubset NCIT_C128784 @default.
- NCIT_C96040 inSubset NCIT_C176424 @default.
- NCIT_C96040 type Class @default.
- NCIT_C96040 isDefinedBy ncit.owl @default.
- NCIT_C96040 label "Anti-OX40 Monoclonal Antibody" @default.
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- NCIT_C96040 subClassOf NCIT_C96040 @default.