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- NCIT_C961 IAO_0000115 "The hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis." @default.
- NCIT_C961 NCIT_A32 NCIT_C1909 @default.
- NCIT_C961 NCIT_A6 NCIT_C66876 @default.
- NCIT_C961 NCIT_A7 NCIT_C17101 @default.
- NCIT_C961 NCIT_NHC0 "C961" @default.
- NCIT_C961 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C961 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C961 NCIT_P107 "Gemcitabine Hydrochloride" @default.
- NCIT_C961 NCIT_P108 "Gemcitabine Hydrochloride" @default.
- NCIT_C961 NCIT_P175 "613327" @default.
- NCIT_C961 NCIT_P207 "C0771488" @default.
- NCIT_C961 NCIT_P210 "122111-03-9" @default.
- NCIT_C961 NCIT_P302 "Bladder cancer; Breast cancer; Carcinoma of unknown primary origin; Lung cancer; including non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Renal cell carcinoma" @default.
- NCIT_C961 NCIT_P319 "U347PV74IL" @default.
- NCIT_C961 NCIT_P322 "CTRP" @default.
- NCIT_C961 NCIT_P322 "FDA" @default.
- NCIT_C961 NCIT_P322 "GDC" @default.
- NCIT_C961 NCIT_P325 "A drug used to treat pancreatic cancer that is advanced or has spread. It is also used with other drugs to treat breast cancer that has spread, advanced ovarian cancer, and non-small cell lung cancer that is advanced or has spread. It is also being studied in the treatment of other types of cancer. Gemcitabine hydrochloride blocks the cell from making DNA and may kill cancer cells." @default.
- NCIT_C961 NCIT_P329 "41213" @default.
- NCIT_C961 NCIT_P330 "41213" @default.
- NCIT_C961 NCIT_P350 "C9H11F2N3O4.HCl" @default.
- NCIT_C961 NCIT_P366 "Gemcitabine" @default.
- NCIT_C961 NCIT_P368 "CHEBI:31647" @default.
- NCIT_C961 NCIT_P375 "Gemcitabine Hydrochloride" @default.
- NCIT_C961 NCIT_P399 "41213" @default.
- NCIT_C961 NCIT_R124 NCIT_C17710 @default.
- NCIT_C961 NCIT_R124 NCIT_C17828 @default.
- NCIT_C961 NCIT_R124 NCIT_C28498 @default.
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- NCIT_C961 NCIT_R125 NCIT_C17702 @default.
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- NCIT_C961 NCIT_R125 NCIT_C20480 @default.
- NCIT_C961 NCIT_R125 NCIT_C21080 @default.
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- NCIT_C961 NCIT_R125 NCIT_C28498 @default.
- NCIT_C961 NCIT_R125 NCIT_C40664 @default.
- NCIT_C961 NCIT_R125 NCIT_C40715 @default.
- NCIT_C961 NCIT_R125 NCIT_C41515 @default.
- NCIT_C961 NCIT_R125 NCIT_C41543 @default.
- NCIT_C961 NCIT_R125 NCIT_C41545 @default.
- NCIT_C961 NCIT_R125 NCIT_C51037 @default.
- NCIT_C961 NCIT_R146 NCIT_C17101 @default.
- NCIT_C961 NCIT_R146 NCIT_C21176 @default.
- NCIT_C961 NCIT_R146 NCIT_C26548 @default.
- NCIT_C961 normalizedInformationContent "68.602014802415724" @default.
- NCIT_C961 referenceCount "115" @default.
- NCIT_C961 hasExactSynonym "1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose, hydrochloride" @default.
- NCIT_C961 hasExactSynonym "2'Deoxy-2',2'-Difluorocytidine, Hydrochloride" @default.
- NCIT_C961 hasExactSynonym "Difluorodeoxycytidine Hydrochloride" @default.
- NCIT_C961 hasExactSynonym "GEMCITABINE HYDROCHLORIDE" @default.
- NCIT_C961 hasExactSynonym "Gemcitabine HCI" @default.
- NCIT_C961 hasExactSynonym "Gemcitabine Hydrochloride" @default.
- NCIT_C961 hasExactSynonym "Gemzar" @default.
- NCIT_C961 hasExactSynonym "LY-188011" @default.
- NCIT_C961 hasExactSynonym "LY188011" @default.
- NCIT_C961 hasExactSynonym "dFdCyd" @default.
- NCIT_C961 hasExactSynonym "gemcitabine hydrochloride" @default.
- NCIT_C961 inSubset NCIT_C116977 @default.
- NCIT_C961 inSubset NCIT_C116978 @default.
- NCIT_C961 inSubset NCIT_C128784 @default.
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- NCIT_C961 inSubset NCIT_C176424 @default.
- NCIT_C961 inSubset NCIT_C177537 @default.
- NCIT_C961 inSubset NCIT_C63923 @default.
- NCIT_C961 type Class @default.
- NCIT_C961 isDefinedBy ncit.owl @default.
- NCIT_C961 label "Gemcitabine Hydrochloride" @default.
- NCIT_C961 subClassOf B05b908e085960a8ce581f30c1b35017c @default.
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