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- NCIT_C965 IAO_0000115 "An orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis. (NCI04)" @default.
- NCIT_C965 NCIT_A32 NCIT_C1909 @default.
- NCIT_C965 NCIT_A7 NCIT_C17219 @default.
- NCIT_C965 NCIT_A7 NCIT_C38361 @default.
- NCIT_C965 NCIT_NHC0 "C965" @default.
- NCIT_C965 NCIT_P106 "Organic Chemical" @default.
- NCIT_C965 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C965 NCIT_P107 "2-Methoxyestradiol" @default.
- NCIT_C965 NCIT_P108 "2-Methoxyestradiol" @default.
- NCIT_C965 NCIT_P175 "659853" @default.
- NCIT_C965 NCIT_P207 "C0046319" @default.
- NCIT_C965 NCIT_P210 "362-07-2" @default.
- NCIT_C965 NCIT_P319 "6I2QW73SR5" @default.
- NCIT_C965 NCIT_P322 "CTRP" @default.
- NCIT_C965 NCIT_P322 "FDA" @default.
- NCIT_C965 NCIT_P322 "GDC" @default.
- NCIT_C965 NCIT_P325 "2ME2. A drug derived from estrogen that belongs to the family of drugs called angiogenesis inhibitors. It prevents the formation of new blood vessels that tumors need in order to grow." @default.
- NCIT_C965 NCIT_P329 "38472" @default.
- NCIT_C965 NCIT_P330 "38472" @default.
- NCIT_C965 NCIT_P350 "C19H26O3" @default.
- NCIT_C965 NCIT_P366 "_2-Methoxyestradiol" @default.
- NCIT_C965 NCIT_P368 "CHEBI:28955" @default.
- NCIT_C965 NCIT_P375 "2-Methoxyestradiol" @default.
- NCIT_C965 NCIT_P399 "38472" @default.
- NCIT_C965 NCIT_R124 NCIT_C17828 @default.
- NCIT_C965 NCIT_R124 NCIT_C20480 @default.
- NCIT_C965 NCIT_R124 NCIT_C40795 @default.
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- NCIT_C965 NCIT_R125 NCIT_C16864 @default.
- NCIT_C965 NCIT_R125 NCIT_C17356 @default.
- NCIT_C965 NCIT_R125 NCIT_C17828 @default.
- NCIT_C965 NCIT_R125 NCIT_C17932 @default.
- NCIT_C965 NCIT_R125 NCIT_C18081 @default.
- NCIT_C965 NCIT_R125 NCIT_C20150 @default.
- NCIT_C965 NCIT_R125 NCIT_C20349 @default.
- NCIT_C965 NCIT_R125 NCIT_C20480 @default.
- NCIT_C965 NCIT_R125 NCIT_C20751 @default.
- NCIT_C965 NCIT_R125 NCIT_C21102 @default.
- NCIT_C965 NCIT_R125 NCIT_C21124 @default.
- NCIT_C965 NCIT_R125 NCIT_C21128 @default.
- NCIT_C965 NCIT_R125 NCIT_C21147 @default.
- NCIT_C965 NCIT_R125 NCIT_C26044 @default.
- NCIT_C965 NCIT_R125 NCIT_C40715 @default.
- NCIT_C965 NCIT_R125 NCIT_C40775 @default.
- NCIT_C965 NCIT_R125 NCIT_C40777 @default.
- NCIT_C965 NCIT_R125 NCIT_C41515 @default.
- NCIT_C965 NCIT_R125 NCIT_C51037 @default.
- NCIT_C965 NCIT_R72 NCIT_C12219 @default.
- NCIT_C965 NCIT_R72 NCIT_C12508 @default.
- NCIT_C965 NCIT_R72 NCIT_C12555 @default.
- NCIT_C965 NCIT_R72 NCIT_C12865 @default.
- NCIT_C965 NCIT_R72 NCIT_C21599 @default.
- NCIT_C965 normalizedInformationContent "100" @default.
- NCIT_C965 referenceCount "1" @default.
- NCIT_C965 hasExactSynonym "(17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol" @default.
- NCIT_C965 hasExactSynonym "2-METHOXYESTRADIOL" @default.
- NCIT_C965 hasExactSynonym "2-MeE2" @default.
- NCIT_C965 hasExactSynonym "2-MeOE2" @default.
- NCIT_C965 hasExactSynonym "2-Methoxy Estradiol" @default.
- NCIT_C965 hasExactSynonym "2-Methoxyestradiol" @default.
- NCIT_C965 hasExactSynonym "2-methoxyestradiol" @default.
- NCIT_C965 hasExactSynonym "2ME2" @default.
- NCIT_C965 hasExactSynonym "Panzem" @default.
- NCIT_C965 inSubset NCIT_C116977 @default.
- NCIT_C965 inSubset NCIT_C116978 @default.
- NCIT_C965 inSubset NCIT_C128784 @default.
- NCIT_C965 inSubset NCIT_C142799 @default.
- NCIT_C965 inSubset NCIT_C157711 @default.
- NCIT_C965 inSubset NCIT_C157712 @default.
- NCIT_C965 inSubset NCIT_C176424 @default.
- NCIT_C965 inSubset NCIT_C177537 @default.
- NCIT_C965 inSubset NCIT_C63923 @default.
- NCIT_C965 type Class @default.
- NCIT_C965 isDefinedBy ncit.owl @default.
- NCIT_C965 label "2-Methoxyestradiol" @default.
- NCIT_C965 subClassOf NCIT_C129818 @default.
- NCIT_C965 subClassOf NCIT_C147908 @default.
- NCIT_C965 subClassOf NCIT_C163758 @default.
- NCIT_C965 subClassOf NCIT_C1821 @default.
- NCIT_C965 subClassOf NCIT_C1892 @default.
- NCIT_C965 subClassOf NCIT_C1908 @default.
- NCIT_C965 subClassOf NCIT_C1909 @default.
- NCIT_C965 subClassOf NCIT_C1913 @default.
- NCIT_C965 subClassOf NCIT_C274 @default.
- NCIT_C965 subClassOf NCIT_C481 @default.
- NCIT_C965 subClassOf NCIT_C483 @default.
- NCIT_C965 subClassOf NCIT_C547 @default.
- NCIT_C965 subClassOf NCIT_C548 @default.
- NCIT_C965 subClassOf NCIT_C616 @default.
- NCIT_C965 subClassOf NCIT_C718 @default.
- NCIT_C965 subClassOf NCIT_C843 @default.
- NCIT_C965 subClassOf NCIT_C965 @default.
- NCIT_C965 equivalentClass B0273da6390c552b45f9dc10a5c410dfb @default.
- NCIT_C965 equivalentClass B1bda463dd077b89d304ee5c0889ef914 @default.