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- NCIT_C966 IAO_0000115 "A chlorinated methotrexate derivative. Dichloromethotrexate inhibits the enzyme dihydrofolate reductase, thereby preventing the synthesis of purine nucleotides and thymidylates and inhibiting DNA and RNA synthesis. This agent is metabolized and excreted by the liver. (NCI04)" @default.
- NCIT_C966 NCIT_NHC0 "C966" @default.
- NCIT_C966 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C966 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C966 NCIT_P108 "Dichloromethotrexate" @default.
- NCIT_C966 NCIT_P175 "29630" @default.
- NCIT_C966 NCIT_P207 "C0046764" @default.
- NCIT_C966 NCIT_P210 "528-74-5" @default.
- NCIT_C966 NCIT_P319 "29NS58S465" @default.
- NCIT_C966 NCIT_P322 "FDA" @default.
- NCIT_C966 NCIT_P329 "39217" @default.
- NCIT_C966 NCIT_P330 "39217" @default.
- NCIT_C966 NCIT_P366 "Dichloromethotrexate" @default.
- NCIT_C966 NCIT_P399 "39217" @default.
- NCIT_C966 normalizedInformationContent "100" @default.
- NCIT_C966 referenceCount "1" @default.
- NCIT_C966 hasExactSynonym "3', 5'-Dichloroamethopterin" @default.
- NCIT_C966 hasExactSynonym "3',5'-Dichloroamethopterin" @default.
- NCIT_C966 hasExactSynonym "3',5'-Dichloromethotrexate" @default.
- NCIT_C966 hasExactSynonym "3'-5'-Dichloromethotrexate" @default.
- NCIT_C966 hasExactSynonym "3,5-Dichloromethotrexate" @default.
- NCIT_C966 hasExactSynonym "Amethopterin, 3',5'-dichloro" @default.
- NCIT_C966 hasExactSynonym "Amethopterin, 3',5'-dichloro-" @default.
- NCIT_C966 hasExactSynonym "DCM" @default.
- NCIT_C966 hasExactSynonym "DICHLOROMETHOTREXATE" @default.
- NCIT_C966 hasExactSynonym "Dichloroamethopterin" @default.
- NCIT_C966 hasExactSynonym "Dichloromethotrexate" @default.
- NCIT_C966 hasExactSynonym "Glutamic Acid, N-{3,5-dichloro-4-{[(2,4-diamino-6-pteridinyl)methyl]methylamino}benzoyl}-" @default.
- NCIT_C966 hasExactSynonym "Glutamic Acid, N-{3,5-dichloro-4-{[(2,4-diamino-6-pteridinyl)methyl]methylamino}benzoyl}-L- (8CI)" @default.
- NCIT_C966 hasExactSynonym "Glutamic acid, N-(3,5-dichloro-4-([(2, 4-diamino-6-pteridinyl)methyl]methylamino)benzoyl)-" @default.
- NCIT_C966 hasExactSynonym "Glutamic acid, N-[3,5-dichloro-4-[[(2, 4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-" @default.
- NCIT_C966 hasExactSynonym "Glutamic acid, N-[3,5-dichloro-4-[[(2, 4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L- (8CI)" @default.
- NCIT_C966 hasExactSynonym "L-Glutamic Acid, N-{3,5-dichloro-4-{[(2,4-diamino-6-pteridinyl)methyl]methylamino}benzoyl}-(9CI)" @default.
- NCIT_C966 hasExactSynonym "L-Glutamic acid, N-[3,5-dichloro-4-[[(2, 4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI)" @default.
- NCIT_C966 hasExactSynonym "Methotrexate, Dichloro" @default.
- NCIT_C966 hasExactSynonym "Methotrexate, dichloro-" @default.
- NCIT_C966 hasExactSynonym "N-[3,5-Dichloro-4-[(2, 4-diamino-6-pteridinylmethyl)methylamino]benzoyl]glutamic acid" @default.
- NCIT_C966 hasExactSynonym "N-[3,5-Dichloro-4-[(2,4-diamino-6-pteridinylmethyl)methylamino]benzoyl] Glutamic Acid" @default.
- NCIT_C966 inSubset NCIT_C176424 @default.
- NCIT_C966 inSubset NCIT_C63923 @default.
- NCIT_C966 type Class @default.
- NCIT_C966 isDefinedBy ncit.owl @default.
- NCIT_C966 label "Dichloromethotrexate" @default.
- NCIT_C966 subClassOf NCIT_C186664 @default.
- NCIT_C966 subClassOf NCIT_C1908 @default.
- NCIT_C966 subClassOf NCIT_C1909 @default.
- NCIT_C966 subClassOf NCIT_C2153 @default.
- NCIT_C966 subClassOf NCIT_C272 @default.
- NCIT_C966 subClassOf NCIT_C274 @default.
- NCIT_C966 subClassOf NCIT_C471 @default.
- NCIT_C966 subClassOf NCIT_C511 @default.
- NCIT_C966 subClassOf NCIT_C966 @default.