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- NCIT_C97034 IAO_0000115 "A pentavalent vaccine comprised of the epitope antigens of the ganglioside lactones GD2L and GD3L, Globo H hexasaccharide 1 (Globo H), fucosyl GM1 and N-propionylated polysialic acid conjugated with the immunostimulant keyhole limpet hemocyanin (KLH), with potential immunostimulating and antineoplastic activity. Vaccination with the pentavalent KLH conjugate vaccine may induce production of IgG and IgM antibodies as well as an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing any of these antigens. The antigens included in the pentavalent KLH conjugate vaccine are upregulated in a variety of cancer cells. KLH, a natural protein isolated from the marine mollusk keyhole limpet, is an immunostimulant carrier protein." @default.
- NCIT_C97034 NCIT_A7 NCIT_C1110 @default.
- NCIT_C97034 NCIT_A7 NCIT_C1201 @default.
- NCIT_C97034 NCIT_A7 NCIT_C126893 @default.
- NCIT_C97034 NCIT_A7 NCIT_C126894 @default.
- NCIT_C97034 NCIT_A7 NCIT_C39782 @default.
- NCIT_C97034 NCIT_NHC0 "C97034" @default.
- NCIT_C97034 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C97034 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C97034 NCIT_P107 "Pentavalent KLH Conjugate Vaccine" @default.
- NCIT_C97034 NCIT_P108 "Pentavalent KLH Conjugate Vaccine" @default.
- NCIT_C97034 NCIT_P208 "CL429641" @default.
- NCIT_C97034 NCIT_P322 "CTRP" @default.
- NCIT_C97034 NCIT_P329 "700447" @default.
- NCIT_C97034 NCIT_P330 "700447" @default.
- NCIT_C97034 NCIT_P399 "700447" @default.
- NCIT_C97034 normalizedInformationContent "100" @default.
- NCIT_C97034 referenceCount "1" @default.
- NCIT_C97034 hasExactSynonym "Pentavalent KLH Conjugate Vaccine" @default.
- NCIT_C97034 inSubset NCIT_C116977 @default.
- NCIT_C97034 inSubset NCIT_C116978 @default.
- NCIT_C97034 inSubset NCIT_C128784 @default.
- NCIT_C97034 inSubset NCIT_C176424 @default.
- NCIT_C97034 type Class @default.
- NCIT_C97034 isDefinedBy ncit.owl @default.
- NCIT_C97034 label "Pentavalent KLH Conjugate Vaccine" @default.
- NCIT_C97034 subClassOf NCIT_C129820 @default.
- NCIT_C97034 subClassOf NCIT_C1455 @default.
- NCIT_C97034 subClassOf NCIT_C1663 @default.
- NCIT_C97034 subClassOf NCIT_C1908 @default.
- NCIT_C97034 subClassOf NCIT_C1909 @default.
- NCIT_C97034 subClassOf NCIT_C274 @default.
- NCIT_C97034 subClassOf NCIT_C307 @default.
- NCIT_C97034 subClassOf NCIT_C308 @default.
- NCIT_C97034 subClassOf NCIT_C923 @default.
- NCIT_C97034 subClassOf NCIT_C97034 @default.