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- NCIT_C98086 IAO_0000115 "Any inhibitor of the proline-specific serine protease dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. DPP-4 inhibitors bind to DPP-4 and inhibit the breakdown of the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). This prolongs incretin activity, increases postprandial insulin release, decreases glucagon release, delays gastric emptying and lowers blood glucose levels. The risk for hypoglycemia is negligible with the use of DPP-4 inhibitors." @default.
- NCIT_C98086 NCIT_NHC0 "C98086" @default.
- NCIT_C98086 NCIT_P106 "Chemical Viewed Functionally" @default.
- NCIT_C98086 NCIT_P108 "Dipeptidyl Peptidase-4 Inhibitor" @default.
- NCIT_C98086 NCIT_P207 "C1827106" @default.
- NCIT_C98086 normalizedInformationContent "77.276749909527013" @default.
- NCIT_C98086 referenceCount "31" @default.
- NCIT_C98086 hasExactSynonym "DPP-4 Inhibitor" @default.
- NCIT_C98086 hasExactSynonym "Dipeptidyl Peptidase-4 Inhibitor" @default.
- NCIT_C98086 type Class @default.
- NCIT_C98086 isDefinedBy ncit.owl @default.
- NCIT_C98086 label "Dipeptidyl Peptidase-4 Inhibitor" @default.
- NCIT_C98086 subClassOf NCIT_C1908 @default.
- NCIT_C98086 subClassOf NCIT_C1909 @default.
- NCIT_C98086 subClassOf NCIT_C29711 @default.
- NCIT_C98086 subClassOf NCIT_C471 @default.
- NCIT_C98086 subClassOf NCIT_C78276 @default.
- NCIT_C98086 subClassOf NCIT_C783 @default.
- NCIT_C98086 subClassOf NCIT_C98086 @default.