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- NCIT_C982 IAO_0000115 "A chlorinated heterocyclic sulfanilamide with potential antineoplastic activity and potential immunosuppressive activity. Chloroquinoxaline sulfonamide poisons topoisomerase II alpha and topoisomerase II beta, thereby causing double-stranded breaks in DNA, accumulation of unrepaired DNA, and apoptosis. This agent also exhibits lymphotoxicity by inhibiting lymphocyte activation in a cell cycle-specific manner. (NCI04)" @default.
- NCIT_C982 NCIT_A32 NCIT_C1909 @default.
- NCIT_C982 NCIT_NHC0 "C982" @default.
- NCIT_C982 NCIT_P106 "Organic Chemical" @default.
- NCIT_C982 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C982 NCIT_P108 "Chloroquinoxaline Sulfonamide" @default.
- NCIT_C982 NCIT_P175 "339004" @default.
- NCIT_C982 NCIT_P207 "C0049111" @default.
- NCIT_C982 NCIT_P210 "97919-22-7" @default.
- NCIT_C982 NCIT_P319 "O0408QB48D" @default.
- NCIT_C982 NCIT_P322 "FDA" @default.
- NCIT_C982 NCIT_P322 "GDC" @default.
- NCIT_C982 NCIT_P325 "A substance being studied in the treatment of cancer. It is a type of topoisomerase inhibitor." @default.
- NCIT_C982 NCIT_P329 "41055" @default.
- NCIT_C982 NCIT_P330 "41055" @default.
- NCIT_C982 NCIT_P366 "Chloroquinoxaline_Sulfonamide" @default.
- NCIT_C982 NCIT_P375 "Chloroquinoxaline Sulfonamide" @default.
- NCIT_C982 NCIT_P399 "41055" @default.
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- NCIT_C982 NCIT_R146 NCIT_C16554 @default.
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- NCIT_C982 NCIT_R146 NCIT_C20646 @default.
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- NCIT_C982 normalizedInformationContent "100" @default.
- NCIT_C982 referenceCount "1" @default.
- NCIT_C982 hasExactSynonym "Benzenesulfonamide, 4-amino-N-(5-chloro-2-quinoxalinyl)-" @default.
- NCIT_C982 hasExactSynonym "Benzenesulfonamide, 4-amino-N-[5-chloro-2-quinoxalinyl]-" @default.
- NCIT_C982 hasExactSynonym "CHLORSULFAQUINOXALINE" @default.
- NCIT_C982 hasExactSynonym "CQS" @default.
- NCIT_C982 hasExactSynonym "Chloroquinoxaline Sulfonamide" @default.
- NCIT_C982 hasExactSynonym "Chloroquinoxaline sulfonamide" @default.
- NCIT_C982 hasExactSynonym "Chlorsulfaquinoxaline" @default.
- NCIT_C982 hasExactSynonym "chloroquinoxaline sulfonamide" @default.
- NCIT_C982 hasExactSynonym "chlorosulfaquinoxaline" @default.
- NCIT_C982 inSubset NCIT_C128784 @default.
- NCIT_C982 inSubset NCIT_C157711 @default.
- NCIT_C982 inSubset NCIT_C157712 @default.
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- NCIT_C982 inSubset NCIT_C63923 @default.
- NCIT_C982 type Class @default.
- NCIT_C982 isDefinedBy ncit.owl @default.
- NCIT_C982 label "Chloroquinoxaline Sulfonamide" @default.
- NCIT_C982 subClassOf B02997c1d241060683b6e1d9447cb17b9 @default.
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