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- NCIT_C985 IAO_0000115 "An orally-active metabolite of the synthetic aromatic retinoic acid agent etretinate with potential antineoplastic, chemopreventive, anti-psoratic, and embryotoxic properties. Acitretin activates nuclear retinoic acid receptors (RAR), resulting in induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells. This agent may also inhibit tumor angiogenesis. (NCI04)" @default.
- NCIT_C985 NCIT_A32 NCIT_C1909 @default.
- NCIT_C985 NCIT_NHC0 "C985" @default.
- NCIT_C985 NCIT_P106 "Organic Chemical" @default.
- NCIT_C985 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C985 NCIT_P108 "Acitretin" @default.
- NCIT_C985 NCIT_P207 "C0050559" @default.
- NCIT_C985 NCIT_P210 "55079-83-9" @default.
- NCIT_C985 NCIT_P302 "Psoriasis; cutaneous T-cell lymphoma" @default.
- NCIT_C985 NCIT_P319 "LCH760E9T7" @default.
- NCIT_C985 NCIT_P322 "FDA" @default.
- NCIT_C985 NCIT_P322 "GDC" @default.
- NCIT_C985 NCIT_P325 "A substance that is used in the prevention of cancer and in the treatment of psoriasis. It belongs to the family of drugs called retinoids." @default.
- NCIT_C985 NCIT_P329 "43244" @default.
- NCIT_C985 NCIT_P330 "43244" @default.
- NCIT_C985 NCIT_P350 "C21H26O3" @default.
- NCIT_C985 NCIT_P366 "Acitretin" @default.
- NCIT_C985 NCIT_P368 "CHEBI:50173" @default.
- NCIT_C985 NCIT_P375 "Acitretin" @default.
- NCIT_C985 NCIT_P399 "43244" @default.
- NCIT_C985 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C985 referenceCount "2" @default.
- NCIT_C985 hasExactSynonym "(All-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid" @default.
- NCIT_C985 hasExactSynonym "ACITRETIN" @default.
- NCIT_C985 hasExactSynonym "Acitretin" @default.
- NCIT_C985 hasExactSynonym "Etretin" @default.
- NCIT_C985 hasExactSynonym "Neotigason" @default.
- NCIT_C985 hasExactSynonym "Ro 10-1670" @default.
- NCIT_C985 hasExactSynonym "Ro-10-1670" @default.
- NCIT_C985 hasExactSynonym "Soriatane" @default.
- NCIT_C985 hasExactSynonym "Trimethylmethoxyphenyl-retinoic acid" @default.
- NCIT_C985 hasExactSynonym "acitretin" @default.
- NCIT_C985 inSubset NCIT_C128784 @default.
- NCIT_C985 inSubset NCIT_C157711 @default.
- NCIT_C985 inSubset NCIT_C157712 @default.
- NCIT_C985 inSubset NCIT_C176424 @default.
- NCIT_C985 inSubset NCIT_C177537 @default.
- NCIT_C985 inSubset NCIT_C63923 @default.
- NCIT_C985 type Class @default.
- NCIT_C985 isDefinedBy ncit.owl @default.
- NCIT_C985 label "Acitretin" @default.
- NCIT_C985 subClassOf NCIT_C129820 @default.
- NCIT_C985 subClassOf NCIT_C163758 @default.
- NCIT_C985 subClassOf NCIT_C1908 @default.
- NCIT_C985 subClassOf NCIT_C1909 @default.
- NCIT_C985 subClassOf NCIT_C1934 @default.
- NCIT_C985 subClassOf NCIT_C2122 @default.
- NCIT_C985 subClassOf NCIT_C274 @default.
- NCIT_C985 subClassOf NCIT_C308 @default.
- NCIT_C985 subClassOf NCIT_C804 @default.
- NCIT_C985 subClassOf NCIT_C985 @default.