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- NCIT_C99116 IAO_0000115 "A cancer vaccine containing autologous dendritic cells (DCs) that are pulsed with mRNA encoding human telomerase reverse transcriptase (hTERT) and survivin peptide, with potential immunostimulatory and antineoplastic activities. Upon administration, hTERT mRNA/survivin peptide-double-loaded autologous dendritic cell vaccine may elicit an immune response against cancer cells expressing hTERT and survivin by activating cytotoxic T-cells (CTLs), natural killer cells (NKs), and B-lymphocytes. The tumor associated antigens (TAAs) hTERT, the catalytic subunit of human telomerase, and survivin, a member of the inhibitor of apoptosis (IAP) family of proteins, may be upregulated in certain tumor cell types and play key roles in tumor cell growth and survival." @default.
- NCIT_C99116 NCIT_NHC0 "C99116" @default.
- NCIT_C99116 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C99116 NCIT_P108 "hTERT mRNA/Survivin Peptide-double-loaded Autologous Dendritic Cell Vaccine" @default.
- NCIT_C99116 NCIT_P208 "CL432938" @default.
- NCIT_C99116 NCIT_P329 "715580" @default.
- NCIT_C99116 NCIT_P330 "715580" @default.
- NCIT_C99116 NCIT_P399 "715580" @default.
- NCIT_C99116 normalizedInformationContent "100" @default.
- NCIT_C99116 referenceCount "1" @default.
- NCIT_C99116 hasExactSynonym "Procure" @default.
- NCIT_C99116 hasExactSynonym "hTERT mRNA/Survivin Peptide-double-loaded Autologous Dendritic Cell Vaccine" @default.
- NCIT_C99116 inSubset NCIT_C128784 @default.
- NCIT_C99116 inSubset NCIT_C176424 @default.
- NCIT_C99116 type Class @default.
- NCIT_C99116 isDefinedBy ncit.owl @default.
- NCIT_C99116 label "hTERT mRNA/Survivin Peptide-double-loaded Autologous Dendritic Cell Vaccine" @default.
- NCIT_C99116 subClassOf NCIT_C129820 @default.
- NCIT_C99116 subClassOf NCIT_C1663 @default.
- NCIT_C99116 subClassOf NCIT_C172787 @default.
- NCIT_C99116 subClassOf NCIT_C181141 @default.
- NCIT_C99116 subClassOf NCIT_C1908 @default.
- NCIT_C99116 subClassOf NCIT_C1909 @default.
- NCIT_C99116 subClassOf NCIT_C274 @default.
- NCIT_C99116 subClassOf NCIT_C28308 @default.
- NCIT_C99116 subClassOf NCIT_C28310 @default.
- NCIT_C99116 subClassOf NCIT_C307 @default.
- NCIT_C99116 subClassOf NCIT_C308 @default.
- NCIT_C99116 subClassOf NCIT_C923 @default.
- NCIT_C99116 subClassOf NCIT_C99116 @default.