Matches in Ubergraph for { <http://purl.obolibrary.org/obo/SO_0000815> ?p ?o ?g. }
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- SO_0000815 IAO_0000115 "By definition, minigenes are short open-reading frames (ORF), usually encoding approximately 9 to 20 amino acids, which are expressed in vivo (as distinct from being synthesized as peptide or protein ex vivo and subsequently injected). The in vivo synthesis confers a distinct advantage: the expressed sequences can enter both antigen presentation pathways, MHC I (inducing CD8+ T- cells, which are usually cytotoxic T-lymphocytes (CTL)) and MHC II (inducing CD4+ T-cells, usually 'T-helpers' (Th)); and can encounter B-cells, inducing antibody responses. Three main vector approaches have been used to deliver minigenes: viral vectors, bacterial vectors and plasmid DNA." @default.
- SO_0000815 normalizedInformationContent "95.413332725061409" @default.
- SO_0000815 referenceCount "2" @default.
- SO_0000815 hasExactSynonym "mini gene" @default.
- SO_0000815 hasOBONamespace "sequence" @default.
- SO_0000815 id "SO:0000815" @default.
- SO_0000815 type Class @default.
- SO_0000815 isDefinedBy so.owl @default.
- SO_0000815 label "mini_gene" @default.
- SO_0000815 subClassOf BFO_0000001 @default.
- SO_0000815 subClassOf BFO_0000002 @default.
- SO_0000815 subClassOf BFO_0000004 @default.
- SO_0000815 subClassOf BFO_0000040 @default.
- SO_0000815 subClassOf COB_0000006 @default.
- SO_0000815 subClassOf SO_0000001 @default.
- SO_0000815 subClassOf SO_0000110 @default.
- SO_0000815 subClassOf SO_0000236 @default.
- SO_0000815 subClassOf SO_0000717 @default.
- SO_0000815 subClassOf SO_0000815 @default.
- SO_0000815 subClassOf SO_0001410 @default.
- SO_0000815 category ChemicalEntity @default.
- SO_0000815 category ChemicalEntityOrGeneOrGeneProduct @default.
- SO_0000815 category ChemicalEntityOrProteinOrPolypeptide @default.
- SO_0000815 category ChemicalOrDrugOrTreatment @default.
- SO_0000815 category Entity @default.
- SO_0000815 category GenomicEntity @default.
- SO_0000815 category MolecularEntity @default.
- SO_0000815 category NamedThing @default.
- SO_0000815 category NucleicAcidEntity @default.
- SO_0000815 category OntologyClass @default.
- SO_0000815 category PhysicalEssence @default.
- SO_0000815 category PhysicalEssenceOrOccurrent @default.
- SO_0000815 category ThingWithTaxon @default.