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- B0046fa4c7edb109833ad6866c75a34c0 NCIT_P378 "NCI" @default.
- B0046fa4c7edb109833ad6866c75a34c0 type Axiom @default.
- B0046fa4c7edb109833ad6866c75a34c0 annotatedProperty IAO_0000115 @default.
- B0046fa4c7edb109833ad6866c75a34c0 annotatedSource NCIT_C48005 @default.
- B0046fa4c7edb109833ad6866c75a34c0 annotatedTarget "The hydrochloride salt of a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth." @default.