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- B0057f02df712d6fe9b40c6a6bf5d554e NCIT_P378 "NCI" @default.
- B0057f02df712d6fe9b40c6a6bf5d554e type Axiom @default.
- B0057f02df712d6fe9b40c6a6bf5d554e annotatedProperty IAO_0000115 @default.
- B0057f02df712d6fe9b40c6a6bf5d554e annotatedSource NCIT_C40684 @default.
- B0057f02df712d6fe9b40c6a6bf5d554e annotatedTarget "Complement Stabilization inhibits conjugation, transport, oxidation, or proteolysis of complement system proteins; sequentially interacting serum proteins (some serine proteases), their receptors, and related regulatory proteins. Activated by cell-surface bound antibody, immune complexes, or a microbial membrane carbohydrate, complex complement cascades (classical or properdin pathway) generate Membrane Attack Complex, which creates target cell wall pores and lysis. The complement system also plays a role in antibody-dependent cytolysis, anaphylaxis, phagocytosis, opsonization, chemotaxis, and hemolysis." @default.