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- B008bf6c49cea7c6f57a9a67ec38b974d NCIT_P378 "NCI" @default.
- B008bf6c49cea7c6f57a9a67ec38b974d type Axiom @default.
- B008bf6c49cea7c6f57a9a67ec38b974d annotatedProperty IAO_0000115 @default.
- B008bf6c49cea7c6f57a9a67ec38b974d annotatedSource NCIT_C167360 @default.
- B008bf6c49cea7c6f57a9a67ec38b974d annotatedTarget "A prime cancer vaccine comprised of a genetically engineered, replication-deficient adenovirus serotype 26 (Ad26) encoding the oncogenic human papillomavirus 16 (HPV16), with potential immunostimulating and antineoplastic activities. Upon intramuscular administration of Ad26-expressing HPV16 vaccine JNJ-63682918, the adenovirus infects and expresses HPV16. The expressed proteins stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing HPV16 antigens, thereby inducing tumor cell lysis. HPV16 infection plays a key role in the development of a variety of cancers." @default.