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- B016bd665c28b03fb773d9c58ced0955f NCIT_P378 "NCI" @default.
- B016bd665c28b03fb773d9c58ced0955f type Axiom @default.
- B016bd665c28b03fb773d9c58ced0955f annotatedProperty IAO_0000115 @default.
- B016bd665c28b03fb773d9c58ced0955f annotatedSource NCIT_C66145 @default.
- B016bd665c28b03fb773d9c58ced0955f annotatedTarget "The sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity. Micafungin, like other cyclic lipopeptides, noncompetitively inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, an enzyme essential for the synthesis of the important fungal cell wall component 1,3-beta-D-glucan. By preventing the synthesis of 1,3-beta-D-glucan, the cell wall is weakened which leads to osmotic lysis and eventually fungal cell death." @default.