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- B033543c4f86d2bfaa892a5f1d7c7c898 NCIT_P378 "NCI" @default.
- B033543c4f86d2bfaa892a5f1d7c7c898 type Axiom @default.
- B033543c4f86d2bfaa892a5f1d7c7c898 annotatedProperty IAO_0000115 @default.
- B033543c4f86d2bfaa892a5f1d7c7c898 annotatedSource NCIT_C61977 @default.
- B033543c4f86d2bfaa892a5f1d7c7c898 annotatedTarget "The sodium salt form of tolmetin, an arylalkanoic acid and non-steroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory and antipyretic activities. Although the exact mechanism through which tolmetin exerts its effects has yet to be fully elucidated, this agent appears to inhibit the enzyme prostaglandin synthase. This prevents the formation of prostaglandins from prostaglandin precursors, including the synthesis of the inflammatory prostaglandin E2 (PGE2) from the precursor prostaglandin H2 (PGH2). This prevents prostaglandin-mediated effects, including pain, inflammation and fever." @default.