Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B0338b35cebb00c302f00c14031dc8c96> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B0338b35cebb00c302f00c14031dc8c96 NCIT_P378 "NCI" @default.
- B0338b35cebb00c302f00c14031dc8c96 type Axiom @default.
- B0338b35cebb00c302f00c14031dc8c96 annotatedProperty IAO_0000115 @default.
- B0338b35cebb00c302f00c14031dc8c96 annotatedSource NCIT_C129710 @default.
- B0338b35cebb00c302f00c14031dc8c96 annotatedTarget "An orally bioavailable, selective inhibitor of Bruton's tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, M7583 targets and covalently binds to BTK, thereby preventing its activity. This leads to an inhibition of B cell receptor (BCR) signaling and inhibits cell proliferation of B-cell malignancies. BTK, a cytoplasmic tyrosine kinase and member of the Tec family of kinases, plays an important role in B lymphocyte development, activation, signaling, proliferation and survival." @default.