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- B04033e3894583ba0d51f04ccf8dc2cf9 NCIT_P378 "NCI" @default.
- B04033e3894583ba0d51f04ccf8dc2cf9 type Axiom @default.
- B04033e3894583ba0d51f04ccf8dc2cf9 annotatedProperty IAO_0000115 @default.
- B04033e3894583ba0d51f04ccf8dc2cf9 annotatedSource NCIT_C47975 @default.
- B04033e3894583ba0d51f04ccf8dc2cf9 annotatedTarget "The hydrochloride salt form of chlorpromazine, a phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine hydrochloride exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, such as hallucinations and delusions. Chlorpromazine hydrochloride appears to exert its anti-emetic activity by blocking the dopamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting." @default.