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- B04ab93af2c3dee1a43c8d3a46669dc81 NCIT_P378 "BIOCARTA" @default.
- B04ab93af2c3dee1a43c8d3a46669dc81 type Axiom @default.
- B04ab93af2c3dee1a43c8d3a46669dc81 annotatedProperty NCIT_P325 @default.
- B04ab93af2c3dee1a43c8d3a46669dc81 annotatedSource NCIT_C39246 @default.
- B04ab93af2c3dee1a43c8d3a46669dc81 annotatedTarget "The T Cell Receptor plays a key role in the immune system. The specificity of the receptor is governed by the binding site formed from the mature alpha and beta chains or gamma and delta chains in gamma/delta T Cells. It is the ability of this receptor to bind a complex of foreign peptide in the groove of an MHC molecule that leads to T cell activation. Upon activation the T cell can assist in activating other cells or carry out cytolytic attacks depending on the particular T cell type. The CD3 complex and CD4 (Th cells) or CD8 (Tc cells) work to transmit the activation signal to the T cell's transcriptional machinery upon engagement of the receptor. (This definition may be outdated - see the DesignNote.)" @default.