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- B04f452b72f357d3c6ad19feb9796b85f NCIT_P378 "NCI" @default.
- B04f452b72f357d3c6ad19feb9796b85f type Axiom @default.
- B04f452b72f357d3c6ad19feb9796b85f annotatedProperty IAO_0000115 @default.
- B04f452b72f357d3c6ad19feb9796b85f annotatedSource NCIT_C1301 @default.
- B04f452b72f357d3c6ad19feb9796b85f annotatedTarget "An enediyne antineoplastic antibiotic hybrid containing an anthranilate moiety. Esperamicin A1 is isolated from the bacterium Actinomadura verrucosospora. The anthranilate component of esperamicin A1 intercalates DNA and the benzene diradical intermediate of the enediyne core binds to the minor groove of DNA, resulting in single- and double-stranded breaks in DNA and apoptosis. (NCI04)" @default.