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- B050cb5d8b21c25a98fe5c90f21060a1d NCIT_P378 "NCI" @default.
- B050cb5d8b21c25a98fe5c90f21060a1d type Axiom @default.
- B050cb5d8b21c25a98fe5c90f21060a1d annotatedProperty IAO_0000115 @default.
- B050cb5d8b21c25a98fe5c90f21060a1d annotatedSource NCIT_C76164 @default.
- B050cb5d8b21c25a98fe5c90f21060a1d annotatedTarget "A semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity. Cefetamet binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis." @default.