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- B05579359fc3ee57769c600e7c63ca1b7 NCIT_P378 "NCI" @default.
- B05579359fc3ee57769c600e7c63ca1b7 type Axiom @default.
- B05579359fc3ee57769c600e7c63ca1b7 annotatedProperty IAO_0000115 @default.
- B05579359fc3ee57769c600e7c63ca1b7 annotatedSource NCIT_C29083 @default.
- B05579359fc3ee57769c600e7c63ca1b7 annotatedTarget "A combination preparation containing guaifenesin and the opioid agonist dextrometorphan with expectorant and antitussive activities, respectively. Guaifenesin works by drawing water into respiratory tracts, by which reducing adhesiveness and surface tension of mucus as well as increasing hydration of mucus, thereby reducing the viscosity of mucus and making cough more productive. Dextrometorphan, a synthetic, methylated dextrorotary analogue of levorphanol, exhibits antitussive activity by activating opioid receptors in the cough center in the central nervous system, thereby raising the threshold for coughing." @default.