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- B05c92d887ab6350091af93ee8b4dafe8 NCIT_P378 "NCI" @default.
- B05c92d887ab6350091af93ee8b4dafe8 type Axiom @default.
- B05c92d887ab6350091af93ee8b4dafe8 annotatedProperty IAO_0000115 @default.
- B05c92d887ab6350091af93ee8b4dafe8 annotatedSource NCIT_C78478 @default.
- B05c92d887ab6350091af93ee8b4dafe8 annotatedTarget "A cancer vaccine consisting of a recombinant form of human melanoma antigen A3 (MAGE-A3) combined with a proprietary adjuvant with potential immunostimulatory and antineoplastic activities. Upon administration, astuprotimut-R may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the MAGE-A3 antigen, resulting in tumor cell death. MAGE-A3, a tumor-associated antigen (TAA) originally discovered in melanoma cells, is expressed by various tumor types. The proprietary immunostimulating adjuvant in this agent is composed of a specific combination of immunostimulating compounds selected to increase the anti-tumor immune response to MAGE-A3." @default.