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- B0630c24a645cd5ef9e1f5bb7dce1de7a date_retrieved "2012-09-17" @default.
- B0630c24a645cd5ef9e1f5bb7dce1de7a external_class "VHOG:0001188" @default.
- B0630c24a645cd5ef9e1f5bb7dce1de7a ontology "VHOG" @default.
- B0630c24a645cd5ef9e1f5bb7dce1de7a source "DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M, Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)" @default.
- B0630c24a645cd5ef9e1f5bb7dce1de7a source "http://bgee.unil.ch/" @default.
- B0630c24a645cd5ef9e1f5bb7dce1de7a type Axiom @default.
- B0630c24a645cd5ef9e1f5bb7dce1de7a annotatedProperty UBPROP_0000003 @default.
- B0630c24a645cd5ef9e1f5bb7dce1de7a annotatedSource UBERON_0001132 @default.
- B0630c24a645cd5ef9e1f5bb7dce1de7a annotatedTarget "The evolution of the tetrapods, and the shift from an aquatic to a terrestrial environment, was believed to have required new controls for regulating calcium homeostasis, and thus the evolution of parathyroid glands (...) both the tetrapod parathyroid and the gills of fish contribute to the regulation of extracellular calcium levels. It is therefore reasonable to suggest that the parathyroid gland evolved as a result of the transformation of the gills into the parathyroid glands of tetrapods and the transition from an aquatic to a terrestrial environment. This interpretation would also explain the positioning of the parathyroid gland within the pharynx in the tetrapod body. Were the parathyroid gland to have emerged de novo with the evolution of the tetrapods it could, as an endocrine organ, have been placed anywhere in the body and still exert its effect.[well established][VHOG]" @default.