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- B07828de86372dff52ea1577d6bc2a57e NCIT_P378 "NCI" @default.
- B07828de86372dff52ea1577d6bc2a57e type Axiom @default.
- B07828de86372dff52ea1577d6bc2a57e annotatedProperty IAO_0000115 @default.
- B07828de86372dff52ea1577d6bc2a57e annotatedSource NCIT_C29083 @default.
- B07828de86372dff52ea1577d6bc2a57e annotatedTarget "A combination preparation containing guaifenesin and the opioid agonist dextrometorphan with expectorant and antitussive activities, respectively. Guaifenesin works by drawing water into respiratory tracts, by which reducing adhesiveness and surface tension of mucus as well as increasing hydration of mucus, thereby reducing the viscosity of mucus and making cough more productive. Dextrometorphan, a synthetic, methylated dextrorotary analogue of levorphanol, exhibits antitussive activity by activating opioid receptors in the cough center in the central nervous system, thereby raising the threshold for coughing." @default.