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- B087c96e7339ec903271fb00afb8669a5 NCIT_P378 "NCI" @default.
- B087c96e7339ec903271fb00afb8669a5 type Axiom @default.
- B087c96e7339ec903271fb00afb8669a5 annotatedProperty IAO_0000115 @default.
- B087c96e7339ec903271fb00afb8669a5 annotatedSource NCIT_C47597 @default.
- B087c96e7339ec903271fb00afb8669a5 annotatedTarget "The sodium salt form of meclofenamate, an anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Meclofenamate sodium inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of meclofenamate sodium. Meclofenamate sodium also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation." @default.