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- B0923907c281c0074da11dc772018b6f9 NCIT_P378 "NCI" @default.
- B0923907c281c0074da11dc772018b6f9 type Axiom @default.
- B0923907c281c0074da11dc772018b6f9 annotatedProperty IAO_0000115 @default.
- B0923907c281c0074da11dc772018b6f9 annotatedSource NCIT_C72656 @default.
- B0923907c281c0074da11dc772018b6f9 annotatedTarget "A semisynthetic beta-lactamase-stable penicillin with antibacterial activity. Fomidacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis." @default.