Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B093fd78bdd8c28504a113108165c5684> ?p ?o ?g. }
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- B093fd78bdd8c28504a113108165c5684 NCIT_P378 "NCI" @default.
- B093fd78bdd8c28504a113108165c5684 type Axiom @default.
- B093fd78bdd8c28504a113108165c5684 annotatedProperty IAO_0000115 @default.
- B093fd78bdd8c28504a113108165c5684 annotatedSource NCIT_C1055 @default.
- B093fd78bdd8c28504a113108165c5684 annotatedTarget "The eicosasodium salt of a mixed-backbone antisense oligodeoxynucleotide with chemosensitizing properties. Custirsen inhibits testosterone-repressed prostate message-2 (TRPM-2). Administration of custirsen abrogates the anti-apoptotic effect of TRPM-2, thereby sensitizing cells to chemotherapy and resulting in tumor cell death. TRPM-2 is an anti-apoptotic clusterin that is overexpressed by prostate cancer cells and is associated with chemoresistance." @default.