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- B0981d93c1a7fe18023010628924d2c8e date_retrieved "2012-09-17" @default.
- B0981d93c1a7fe18023010628924d2c8e external_class "VHOG:0000275" @default.
- B0981d93c1a7fe18023010628924d2c8e ontology "VHOG" @default.
- B0981d93c1a7fe18023010628924d2c8e source "DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)" @default.
- B0981d93c1a7fe18023010628924d2c8e source "http://bgee.unil.ch/" @default.
- B0981d93c1a7fe18023010628924d2c8e type Axiom @default.
- B0981d93c1a7fe18023010628924d2c8e annotatedProperty UBPROP_0000003 @default.
- B0981d93c1a7fe18023010628924d2c8e annotatedSource UBERON_0000019 @default.
- B0981d93c1a7fe18023010628924d2c8e annotatedTarget "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" @default.