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- B0a2b5298b01128a9bd1ec3e6f6352f9e NCIT_P378 "NCI" @default.
- B0a2b5298b01128a9bd1ec3e6f6352f9e type Axiom @default.
- B0a2b5298b01128a9bd1ec3e6f6352f9e annotatedProperty IAO_0000115 @default.
- B0a2b5298b01128a9bd1ec3e6f6352f9e annotatedSource NCIT_C104004 @default.
- B0a2b5298b01128a9bd1ec3e6f6352f9e annotatedTarget "A topical formulation of the hydrochloride salt of the tropane alkaloid cocaine, with local anesthetic activity. Upon topical application of the cocaine hydrochloride solution to nasal mucous membranes, cocaine reversibly binds to and blocks the voltage-gated sodium channels in the neuronal cell membranes. By stabilizing neuronal membranes, cocaine inhibits the initiation and conduction of nerve impulses and produces a reversible loss of sensation." @default.