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- B0a8a4541c31f72f8a5eae0a633cbac41 NCIT_P378 "NCI" @default.
- B0a8a4541c31f72f8a5eae0a633cbac41 type Axiom @default.
- B0a8a4541c31f72f8a5eae0a633cbac41 annotatedProperty IAO_0000115 @default.
- B0a8a4541c31f72f8a5eae0a633cbac41 annotatedSource NCIT_C102877 @default.
- B0a8a4541c31f72f8a5eae0a633cbac41 annotatedTarget "A fully human monoclonal antibody targeting the vascular endothelial growth factor receptor 2 (VEGFR2), with potential antiangiogenic activity. Upon administration, olinvacimab specifically binds to VEGFR2, thereby preventing the binding of its ligand VEGF. This may result in the inhibition of tumor angiogenesis and a decrease in tumor nutrient supply. VEGFR2 is a pro-angiogenic growth factor receptor tyrosine kinase expressed by endothelial cells, while VEGF is overexpressed in many tumors and is correlated to tumor progression." @default.