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- B0bf305719f908cca60d6f1321988d55f NCIT_P378 "NCI" @default.
- B0bf305719f908cca60d6f1321988d55f type Axiom @default.
- B0bf305719f908cca60d6f1321988d55f annotatedProperty IAO_0000115 @default.
- B0bf305719f908cca60d6f1321988d55f annotatedSource NCIT_C1533 @default.
- B0bf305719f908cca60d6f1321988d55f annotatedTarget "The disodium salt of a synthetic pyrimidine-based antifolate. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis." @default.