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- B0ce9e512c3e140168bff7d9325440ec3 NCIT_P378 "NCI" @default.
- B0ce9e512c3e140168bff7d9325440ec3 type Axiom @default.
- B0ce9e512c3e140168bff7d9325440ec3 annotatedProperty IAO_0000115 @default.
- B0ce9e512c3e140168bff7d9325440ec3 annotatedSource NCIT_C47578 @default.
- B0ce9e512c3e140168bff7d9325440ec3 annotatedTarget "A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation." @default.